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Everything about SIL1
Protein-coding gene in the species Homo sapiens
Nucleotide exchange factor SIL1 is a protein encoded in humans by the SIL1 gene. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: SIL1A 5-minute orientation
- Skim a recent paper: The involvement of systemic RNA interference deficient‐1‐like (SIL1) in cellular dsRNA uptake in Acyrthosiphon pisumInfluential work since 2022
- Pick up a classic book: Fairest of allThe most-reprinted book on the subject
- Read the landmark paper: Mutations in SIL1 cause Marinesco-Sjögren syndrome, a cerebellar ataxia with cataract and myopathyCited 226 times
- Go sideways: Binding immunoglobulin proteinA closely related topic
- Go sideways: Marinesco–Sjögren syndromeA closely related topic
📖 Definitions
No dictionary entry for this exact phrase.
🗂️ The subject at a glance
🏆 Landmark papers (most cited)
Mutations in SIL1 cause Marinesco-Sjögren syndrome, a cerebellar ataxia with cataract and myopathy
The gene disrupted in Marinesco-Sjögren syndrome encodes SIL1, an HSPA5 cochaperone
Protein accumulation and neurodegeneration in the woozy mutant mouse is caused by disruption of SIL1, a cochaperone of BiP
BiP and Its Nucleotide Exchange Factors Grp170 and Sil1: Mechanisms of Action and Biological Functions
LHS1 and SIL1 provide a lumenal function that is essential for protein translocation into the endoplasmic reticulum
SIL1 mutations and clinical spectrum in patients with Marinesco-Sjögren syndrome
Marinesco-Sjögren syndrome protein SIL1 regulates motor neuron subtype-selective ER stress in ALS
Structural analysis of the Sil1–Bip complex reveals the mechanism for Sil1 to function as a nucleotide-exchange factor
🆕 Influential since 2022
The involvement of systemic RNA interference deficient‐1‐like (SIL1) in cellular dsRNA uptake in Acyrthosiphon pisum
Sil1-deficient fibroblasts generate an aberrant extracellular matrix leading to tendon disorganisation in Marinesco-Sjögren syndrome
Selective activation of antioxidant resources and energy deficiency in Marinesco–Sjögren syndrome fibroblasts as an adaptive biological response to Sil1 loss
SIL1 improves cognitive impairment in APP23/PS45 mice by regulating amyloid precursor protein processing and Aβ generation
Exome sequencing revealed variants in SGCA and SIL1 genes underlying limb girdle muscular dystrophy and Marinesco–Sjögren syndrome patients
📚 Books worth reading
Fairest of allSarah Mlynowski · 2012
Jonathan MeeseJonathan Meese · 2004- 📕Nauchnaya konferentsiya geografov i ékonomistov Pribaltiki po teme "Kontseptsii razvitiya i razmeshcheniya proizvoditel'nȳkh sil pribaltiĭskikh soyuznȳkh respublik", rezyume dokladovEesti NSV Teaduste Akadeemia. Majanduse Instituut. · 1973
- 📕Intermed Acctg Sils 1Dyckman · 1991
- 📕Acctg Prin Sils 1Hermanson · 1991
- 📕Intermed Acctg Sils 1/Crm PkgDyckman · 1992
- 📕Fap Sils 1/Spat 1 W/350 Pkg 13Ron Larson · 1994
- 📕Fap Sils 1/Spat 1 W/525 Pkg 13Ron Larson · 1994
Ranked by number of editions on Open Library, a rough measure of how lasting a book is.
🔗 Related topics
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