Everything about Gastroesophageal reflux disease
Flow of stomach contents into the esophagus
Gastroesophageal reflux disease (GERD) or gastro-oesophageal reflux disease (GORD) is a chronic upper gastrointestinal disease in which stomach content persistently and regularly flows up into the esophagus, resulting in symptoms and/or complications. Symptoms include heartburn, acidic taste, and feeling of regurgitation. Other symptoms can include breathing problems, dysphagia, odynophagia, non-cardiac chest pain, dental corrosion, extraesophageal symptoms such as chronic cough, hoarseness, reflux-induced laryngitis, or asthma. In the long term, and when not treated, complications such as esophagitis, esophageal stricture, and Barrett's esophagus may arise. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: Gastroesophageal reflux diseaseA 5-minute orientation
- Skim a recent paper: Effect of Laparoscopic Sleeve Gastrectomy vs Roux-en-Y Gastric Bypass on Weight Loss, Comorbidities, and Reflux at 10 Years in Adult Patients With ObesityInfluential work since 2022
- Pick up a classic book: Tell me what to eat if I have acid refluxThe most-reprinted book on the subject
- Read the landmark paper: The Montreal Definition and Classification of Gastroesophageal Reflux Disease: A Global Evidence-Based ConsensusCited 3,109 times
- Go sideways: HeartburnA closely related topic
- Go sideways: Nissen fundoplicationA closely related topic
📖 Definitions
Noun The backwards flow of any fluid.
Noun A technique, using a reflux condenser, allowing one to boil the contents of a vessel over an extended period.
Noun The leaking of stomach acid up into the oesophagus.
Verb To flow back or return.
🗂️ The subject at a glance
🏆 Landmark papers (most cited)
The Montreal Definition and Classification of Gastroesophageal Reflux Disease: A Global Evidence-Based Consensus
Symptomatic Gastroesophageal Reflux as a Risk Factor for Esophageal Adenocarcinoma
Update on the epidemiology of gastro-oesophageal reflux disease: a systematic review
Prevalence and clinical spectrum of gastroesophageal reflux: A population-based study in Olmsted County, Minnesota
Epidemiology of gastro-oesophageal reflux disease: a systematic review
Guidelines for the Diagnosis and Management of Gastroesophageal Reflux Disease
Validity and Reliability of the Reflux Symptom Index (RSI)
The Otolaryngologic Manifestations of Gastroesophageal Reflux Disease (GERD): A Clinical Investigation of 225 Patients Using Ambulatory 24‐Hour pH Monitoring and an Experimental Investigation of the Role of Acid and Pepsin in the Development of Laryngeal Injury
🆕 Influential since 2022
Effect of Laparoscopic Sleeve Gastrectomy vs Roux-en-Y Gastric Bypass on Weight Loss, Comorbidities, and Reflux at 10 Years in Adult Patients With Obesity
Global, regional and national burden of gastroesophageal reflux disease, 1990–2019: update from the GBD 2019 study
Evidence-based clinical practice guidelines for gastroesophageal reflux disease 2021
The 2022 Society for Vascular Surgery, American Venous Forum, and American Vein and Lymphatic Society clinical practice guidelines for the management of varicose veins of the lower extremities. Part I. Duplex Scanning and Treatment of Superficial Truncal Reflux
The Dubai Definition and Diagnostic Criteria of Laryngopharyngeal Reflux: The IFOS Consensus
📚 Books worth reading
Tell me what to eat if I have acid refluxElaine Magee · 2001
The green olive treeIrene Murray · 1962
Practical Manual of Gastroesophageal Reflux DiseaseMarcelo F. Vela, Joel E. Richter · 2012
Diseases of the Gastroesophageal MucosaJames W. Freston · 2001
50 Ways to Relieve Heartburn, Reflux and UlcersM. Sara Rosenthal · 2001
Antireflux SurgeryLee L. Swanstrom, Christy M. Dunst · 2014- 📕Anti-gastroesophageal reflux implantationDenise Holland · 1983
- 📕24-hour ambulatory esophageal pH monitoringHarry Handelsman · 1985
Ranked by number of editions on Open Library, a rough measure of how lasting a book is.
🔗 Related topics
- Heartburn Heartburn is a burning sensation felt behind the breastbone. It is a symptom that is commonly linked to acid reflux and is often triggered by food. Lying…
- Nissen fundoplication A Nissen fundoplication, or laparoscopic Nissen fundoplication when performed via laparoscopic surgery, is a surgical procedure to treat gastroesophageal…
- Stretta procedure Stretta is a minimally invasive endoscopic procedure for the treatment of gastroesophageal reflux disease (GERD) that delivers radiofrequency energy in…
- Esophageal pH monitoring In gastroenterology, esophageal pH monitoring is the current gold standard for diagnosis of gastroesophageal reflux disease (GERD). It provides direct…
- Hiatal hernia A hiatal hernia or hiatus hernia is a type of hernia in which abdominal organs (typically the stomach) slip through the diaphragm into the middle compartment…
- Esophagitis Esophagitis, also spelled oesophagitis, is a disease characterized by inflammation of the esophagus. The esophagus is a tube composed of a mucosal lining…
- Esophageal achalasia Esophageal achalasia, often referred to simply as achalasia, is a failure of smooth muscle fibers to relax, which can cause the lower esophageal sphincter…
- Laryngopharyngeal reflux Laryngopharyngeal reflux (LPR) or laryngopharyngeal reflux disease (LPRD) is the retrograde flow of gastric contents into the larynx, oropharynx and/or…