Everything about Pir

🧭 Start here: a 6-step reading path

1. Read the overview: PirA 5-minute orientation
2. Skim a recent paper: piR-27222 mediates PM2.5-induced lung cancer by resisting cell PANoptosis through the WTAP/m6A axisInfluential work since 2022
3. Pick up a classic book: Pir Hüseyin'de Naram-Sin stelinin keşfi =The most-reprinted book on the subject
4. Read the landmark paper: Photorhabdus insect-related (Pir) toxin-like genes in a plasmid of Vibrio parahaemolyticus, the causative agent of acute hepatopancreatic necrosis disease (AHPND) of shrimpCited 305 times
5. Go sideways: HursA closely related topic
6. Go sideways: Pir of Pagaro VIA closely related topic

🏆 Landmark papers (most cited)

• Photorhabdus insect-related (Pir) toxin-like genes in a plasmid of Vibrio parahaemolyticus, the causative agent of acute hepatopancreatic necrosis disease (AHPND) of shrimp

  JE Han, KFJ Tang, LH Tran · 2015 · Diseases of Aquatic Organisms · 305 citations

• piR-823, a novel non-coding small RNA, demonstrates in vitro and in vivo tumor suppressive activity in human gastric cancer cells

  Jia Cheng, Hongxia Deng, Bingxiu Xiao · 2012 · Cancer Letters · 258 citations

• Characterization and PCR Detection Of Binary, Pir-Like Toxins from Vibrio parahaemolyticus Isolates that Cause Acute Hepatopancreatic Necrosis Disease (AHPND) in Shrimp

  Ratchanok Sirikharin, Suparat Taengchaiyaphum, Piyachat Sanguanrut · 2015 · PLOS ONE · 214 citations

• The protein identification resource (PIR)

  David G. George, Winona C. Barker, Lois T. Hunt · 1986 · Nucleic Acids Research · 202 citations

• Discriminant Validity of NEO-PIR Facet Scales

  Robert R. McCrae, Paul T. Costa · 1992 · Educational and Psychological Measurement · 185 citations

• The paired Ig-like receptor PIR-B is an inhibitory receptor that recruits the protein-tyrosine phosphatase SHP-1

  Mathieu Bléry, Hiromi Kubagawa, Ching-Cheng Chen · 1998 · Proceedings of the National Academy of Sciences · 167 citations

• A new Plasmodium vivax reference sequence with improved assembly of the subtelomeres reveals an abundance of pir genes

  Sarah Auburn, Ulrike Böhme, Sascha Steinbiss · 2016 · Wellcome Open Research · 164 citations

• Requirement of SH2-containing Protein Tyrosine Phosphatases SHP-1 and SHP-2 for Paired Immunoglobulin-like Receptor B (PIR-B)–mediated Inhibitory Signal

  Akito Maeda, Mari Kurosaki, Masao Ono · 1998 · The Journal of Experimental Medicine · 158 citations

🆕 Influential since 2022

• piR-27222 mediates PM2.5-induced lung cancer by resisting cell PANoptosis through the WTAP/m6A axis

  Wanli Ma, Lin Xu, Yixuan Wang · 2024 · Environment International · 72 citations

• piR-16404 drives ferroptotic liver injury via CASTOR1/mTORC1/GPX4 dysregulation in HepG2 cells and mice: a novel toxicity mechanism of N, N-dimethylformamide

  Wanli Ma, Xiaoyu Huo, Ruoxi Li · 2025 · Archives of Toxicology · 42 citations

• IL11 signaling mediates piR-2158 suppression of cell stemness and angiogenesis in breast cancer

  Qian Zhao, Lu Qian, Yuefan Guo · 2023 · Theranostics · 40 citations

• The serine phosphorylations in the IRS-1 PIR domain abrogate IRS-1 and IR interaction

  Ju Rang Woo, Seung-Hyun Bae, Thomas E. Wales · 2024 · Proceedings of the National Academy of Sciences · 40 citations

• piR-823 inhibits cell apoptosis via modulating mitophagy by binding to PINK1 in colorectal cancer

  Shuling Wang, Xiaoyu Jiang, Xiaoli Xie · 2022 · Cell Death & Disease · 38 citations

📚 Books worth reading

• 📕Pir Hüseyin'de Naram-Sin stelinin keşfi =Jakob Paul Naab · 1934
• 📕Izraztsʹi Mavzoleia Pir-KhuseinaV. A. Krachkovskai︠a︡ · 1946
• 📕Türkiye'de AlevilikMurat Okan · 2004
• The Reality of Spiritual AllegianceImam Ahmad Rida · 2017
• 📕Title index of catalogues of Arabic, Persian & Urdu manuscriptsDargāh Ḥaz̤rat Pīr Muḥammad Shāh Lāʼibrerī aur Rīsarc Siṇtar (Ahmadābād, India) · 2003
• 📕Title index of catalogues of Arabic, Persian & Urdu manuscriptsḤaz̤rat Pīr Muḥammad Shāh Lāʾibrerī aur Rīsarc Sainṭar (Ahmadābād, India) · 2003
• 📕ʻArabī, Fārsī, Urdū mak̲h̲t̤ūt̤āt kī vaz̤āḥatī fihristḤaz̤rat Pīr Muḥammad Shāh Dargāh Sharīf Kutub K̲h̲ānah (Ahmadabad, India) · 1992
• Osmanlı gizli tarihinde Pir Sultan Abdal ve bütün deyişleriHaydar A. Avcı · 2006

Ranked by number of editions on Open Library, a rough measure of how lasting a book is.

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