Everything about PTS

🧭 Start here: a 6-step reading path

1. Read the overview: PTSA 5-minute orientation
2. Skim a recent paper: A phase 3 randomized, double-blind, placebo-controlled study of durvalumab in combination with gemcitabine plus cisplatin (GemCis) in patients (pts) with advanced biliary tract cancer (BTC): TOPAZ-1.Influential work since 2022
3. Pick up a classic book: Der ProceßThe most-reprinted book on the subject
4. Read the landmark paper: CheckMate 459: A randomized, multi-center phase III study of nivolumab (NIVO) vs sorafenib (SOR) as first-line (1L) treatment in patients (pts) with advanced hepatocellular carcinoma (aHCC)Cited 544 times
5. Go sideways: PTA closely related topic
6. Go sideways: PPSA closely related topic

🏆 Landmark papers (most cited)

• CheckMate 459: A randomized, multi-center phase III study of nivolumab (NIVO) vs sorafenib (SOR) as first-line (1L) treatment in patients (pts) with advanced hepatocellular carcinoma (aHCC)

  T. Yau, J.W. Park, R.S. Finn · 2019 · Annals of Oncology · 544 citations

• Extraordinarily Strong Interlayer Interaction in 2D Layered PtS 2

  Yuda Zhao, Jingsi Qiao, Peng Yu · 2016 · Advanced Materials · 536 citations

• Phase 3 randomized, open-label, multicenter study of tremelimumab (T) and durvalumab (D) as first-line therapy in patients (pts) with unresectable hepatocellular carcinoma (uHCC): HIMALAYA.

  Ghassan K. Abou-Alfa, Stephen Lam Chan, Masatoshi Kudo · 2022 · Journal of Clinical Oncology · 361 citations

• Layered Platinum Dichalcogenides (PtS 2 , PtSe 2 , and PtTe 2 ) Electrocatalysis: Monotonic Dependence on the Chalcogen Size

  Xinyi Chia, Ambrosi Adriano, Petr Lazar · 2016 · Advanced Functional Materials · 293 citations

• IMbrave150: Updated overall survival (OS) data from a global, randomized, open-label phase III study of atezolizumab (atezo) + bevacizumab (bev) versus sorafenib (sor) in patients (pts) with unresectable hepatocellular carcinoma (HCC).

  Richard S. Finn, Shukui Qin, Masafumi Ikeda · 2021 · Journal of Clinical Oncology · 281 citations

• Pex14p, a Peroxisomal Membrane Protein Binding Both Receptors of the Two PTS-Dependent Import Pathways

  Markus Albertini, Peter Rehling, Ralf Erdmann · 1997 · Cell · 281 citations

• Impact of primary (1º) tumor location on overall survival (OS) and progression-free survival (PFS) in patients (pts) with metastatic colorectal cancer (mCRC): Analysis of CALGB/SWOG 80405 (Alliance).

  Alan P. Venook, Donna Niedzwiecki, Federico Innocenti · 2016 · Journal of Clinical Oncology · 264 citations

• The Political Terror Scale (PTS): A Re-introduction and a Comparison to CIRI

  Reed M. Wood, Mark Gibney · 2010 · Human Rights Quarterly · 250 citations

🆕 Influential since 2022

• A phase 3 randomized, double-blind, placebo-controlled study of durvalumab in combination with gemcitabine plus cisplatin (GemCis) in patients (pts) with advanced biliary tract cancer (BTC): TOPAZ-1.

  Do-Youn Oh, Aiwu Ruth He, Shukui Qin · 2022 · Journal of Clinical Oncology · 204 citations

• Prevalence of anxiety and post-traumatic stress (PTS) among the parents of babies admitted to neonatal units: A systematic review and meta-analysis

  Reem Malouf, Sian Harrison, Hollie A.L Burton · 2022 · eClinicalMedicine · 150 citations

• Phase 3 MAGNITUDE study: First results of niraparib (NIRA) with abiraterone acetate and prednisone (AAP) as first-line therapy in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC) with and without homologous recombination repair (HRR) gene alterations.

  Kim N. Chi, Dana E. Rathkopf, Matthew Raymond Smith · 2022 · Journal of Clinical Oncology · 116 citations

• Trastuzumab deruxtecan (T-DXd) vs physician’s choice of chemotherapy (TPC) in patients (pts) with hormone receptor-positive (HR+), human epidermal growth factor receptor 2 (HER2)-low or HER2-ultralow metastatic breast cancer (mBC) with prior endocrine therapy (ET): Primary results from DESTINY-Breast06 (DB-06).

  Giuseppe Curigliano, Xichun Hu, Rebecca Alexandra Dent · 2024 · Journal of Clinical Oncology · 111 citations

• LBA20 A randomized, double-blind trial of nivolumab (NIVO) vs placebo (PBO) with neoadjuvant chemotherapy (NACT) followed by adjuvant endocrine therapy (ET) ± NIVO in patients (pts) with high-risk, ER+ HER2− primary breast cancer (BC)

  S. Loi, G. Curigliano, R.F. Salgado · 2023 · Annals of Oncology · 107 citations

📚 Books worth reading

• Der ProceßFranz Kafka · 1825
• FaustJohann Wolfgang von Goethe · 1800
• Der SteppenwolfHermann Hesse · 1927
• SiddharthaHermann Hesse · 1922
• AmerikaFranz Kafka · 1927
• Max Havelaar of de koffijveilingen der Nederlansche handelmaatschappijMultatuli · 1868
• Berlin AlexanderplatzAlfred Döblin · 1929
• Die Dreigroschenoper:= The Threepenny OperaBertolt Brecht · 1955

Ranked by number of editions on Open Library, a rough measure of how lasting a book is.

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