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Everything about PSMC2
Enzyme found in humans
26S protease regulatory subunit 7, also known as 26S proteasome AAA-ATPase subunit Rpt1, is an enzyme that in humans is encoded by the PSMC2 gene This protein is one of the 19 essential subunits of a complete assembled 19S proteasome complex. Six 26S proteasome AAA-ATPase subunits together with four non-ATPase subunits form the base sub complex of 19S regulatory particle for proteasome complex. Wikipedia →
🧠Start here: a 6-step reading path
- Read the overview: PSMC2A 5-minute orientation
- Skim a recent paper: PSMC2 knockdown inhibits the progression of oral squamous cell carcinoma by promoting apoptosis via PI3K/Akt pathwayInfluential work since 2022
- Pick up a classic book: In My Opinion - A History of Crown Law Queensland 1859 – 2009The most-reprinted book on the subject
- Read the landmark paper: PSMC2 is up-regulated in osteosarcoma and regulates osteosarcoma cell proliferation, apoptosis and migrationCited 33 times
- Go sideways: PSMC4A closely related topic
- Go sideways: PSMC5A closely related topic
đź“– Definitions
No dictionary entry for this exact phrase.
🗂️ The subject at a glance
🏆 Landmark papers (most cited)
PSMC2 is up-regulated in osteosarcoma and regulates osteosarcoma cell proliferation, apoptosis and migration
Overexpression of PSMC2 promotes the tumorigenesis and development of human breast cancer via regulating plasminogen activator urokinase (PLAU)
PSMC2 promotes the progression of gastric cancer via induction of RPS15A/mTOR pathway
PSMC2/CCND1 axis promotes development of ovarian cancer through regulating cell growth, apoptosis and migration
PSMC2 is Up-regulated in Pancreatic Cancer and Promotes Cancer Cell Proliferation and Inhibits Apoptosis
PSMC2/ITGA6 axis plays critical role in the development and progression of hepatocellular carcinoma
PSMC2 is overexpressed in glioma and promotes proliferation and anti-apoptosis of glioma cells
Silencing of PSMC2 inhibits development and metastasis of prostate cancer through regulating proliferation, apoptosis and migration
🆕 Influential since 2022
PSMC2 knockdown inhibits the progression of oral squamous cell carcinoma by promoting apoptosis via PI3K/Akt pathway
PSMC2 promotes resistance against temozolomide in glioblastoma via suppressing JNK-mediated autophagic cell death
PSMC2 knockdown exerts an anti-tumor role in nasopharyngeal carcinoma through regulating AKT signaling pathway
PSMC2 promotes glioma progression by regulating immune microenvironment and PI3K/AKT/mTOR pathway
PSMC2 upregulation enhances epithelial-to-mesenchymal transition in glioblastoma via activating AKT/GSK3β/β-catenin axis
đź“š Books worth reading
In My Opinion - A History of Crown Law Queensland 1859 – 2009Lisbeth Elvery, Conrad Lohe, Gerard Sammon and Angus Scott · 2009
Ranked by number of editions on Open Library, a rough measure of how lasting a book is.
đź”— Related topics
- PSMC4 26S protease regulatory subunit 6B, also known as 26S proteasome AAA-ATPase subunit Rpt3, is an enzyme that in humans is encoded by the PSMC4 gene. This…
- PSMC5 26S protease regulatory subunit 8, also known as 26S proteasome AAA-ATPase subunit Rpt6, is an enzyme that in humans is encoded by the PSMC5 gene. This…
- PSMC1 26S protease regulatory subunit 4, also known as 26S proteasome AAA-ATPase subunit Rpt2, is an enzyme that in humans is encoded by the PSMC1 gene. This…
- PSMC3 26S protease regulatory subunit 6A, also known as 26S proteasome AAA-ATPase subunit Rpt5, is an enzyme that in humans is encoded by the PSMC3 gene. This…
- PSMC6 26S protease regulatory subunit S10B, also known as 26S proteasome AAA-ATPase subunit Rpt4, is an enzyme that in humans is encoded by the PSMC6 gene. This…
- PSMD2 26S proteasome non-ATPase regulatory subunit 2, also as known as 26S Proteasome Regulatory Subunit Rpn1 (systematic nomenclature), is an enzyme that in…
- ADRM1 Proteasomal ubiquitin receptor ADRM1 is a protein that in humans is encoded by the ADRM1 gene. Recent evidences on proteasome complex structure confirmed…
- PSMD7 26S proteasome non-ATPase regulatory subunit 7, also known as 26S proteasome non-ATPase subunit Rpn8, is an enzyme that in humans is encoded by the PSMD7…