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Everything about PROSITE

Database of protein domains, families and functional sites

PROSITE is a protein database. It consists of entries describing the protein families, domains and functional sites as well as amino acid patterns and profiles in them. These are manually curated by a team of the Swiss Institute of Bioinformatics and tightly integrated into Swiss-Prot protein annotation. PROSITE was created in 1988 by Amos Bairoch, who directed the group for more than 20 years. Since July 2018, the director of PROSITE and Swiss-Prot is Alan Bridge. Wikipedia →

🧭 Start here: a 6-step reading path

  1. Read the overview: PROSITEA 5-minute orientation
  2. Skim a recent paper: The PROSITE database for protein families, domains, and sitesInfluential work since 2022
  3. Pick up a classic book: PrositThe most-reprinted book on the subject
  4. Read the landmark paper: ScanProsite: detection of PROSITE signature matches and ProRule-associated functional and structural residues in proteinsCited 1,525 times
  5. Go sideways: Amos BairochA closely related topic
  6. Go sideways: InterProA closely related topic

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🗂️ The subject at a glance

  1. Statistics

🏆 Landmark papers (most cited)

🆕 Influential since 2022

📚 Books worth reading

Ranked by number of editions on Open Library, a rough measure of how lasting a book is.

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