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Everything about Nitroso
Class of functional groups with a –N=O group attached
In organic chemistry, nitroso refers to a functional group in which the nitric oxide group is attached to an organic moiety. As such, various nitroso groups can be categorized as C-nitroso compounds, S-nitroso compounds, N-nitroso compounds, and O-nitroso compounds. Wikipedia →
đź§ Start here: a 6-step reading path
- Read the overview: NitrosoA 5-minute orientation
- Skim a recent paper: Association of Dietary Nitrate, Nitrite, and N-Nitroso Compounds Intake and Gastrointestinal Cancers: A Systematic Review and Meta-AnalysisInfluential work since 2022
- Pick up a classic book: The chemistry of the nitro and nitroso groupsThe most-reprinted book on the subject
- Read the landmark paper: A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compoundsCited 2,054 times
- Go sideways: NitrosamineA closely related topic
- Go sideways: Nitrosation and nitrosylationA closely related topic
đź“– Definitions
Noun The univalent radical and functional group -N=O
🗂️ The subject at a glance
🏆 Landmark papers (most cited)
A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds
Organotrope carcinogene Wirkungen bei 65 verschiedenen N-Nitroso-Verbindungen an BD-Ratten
Nitric oxide circulates in mammalian plasma primarily as an S-nitroso adduct of serum albumin.
Role of N-nitroso compounds (NOC) and N-nitrosation in etiology of gastric, esophageal, nasopharyngeal and bladder cancer and contribution to cancer of known exposures to NOC
Formation of N-nitroso compounds: Chemistry, kinetics, and in vivo occurrence
Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-N-methylurea during initiation of mammary carcinogenesis in rats
Induction of mammary carcinomas in rats by nitroso-methylurea involves malignant activation of H-ras-1 locus by single point mutations
Influence of dietary nitrate on nitrite content of human saliva: Possible relevance to in vivo formation of N-nitroso compounds
🆕 Influential since 2022
Association of Dietary Nitrate, Nitrite, and N-Nitroso Compounds Intake and Gastrointestinal Cancers: A Systematic Review and Meta-Analysis
Aquatic arsenic removal with a Zr-MOF constructed via in situ nitroso coupling
Current status and prospects of development of analytical methods for determining nitrosamine and N-nitroso impurities in pharmaceuticals
Nitroso-caged upconversion luminescent prodrug: Near infrared light-activatable NO nano-donor for gas therapy
Revisiting the mutagenicity and genotoxicity of N-nitroso propranolol in bacterial and human in vitro assays
📚 Books worth reading
The chemistry of the nitro and nitroso groupsHenry Feuer · 1969
Alternatives to the Current Use of Nitrite in FoodsAssembly of Life Sciences · 1982- 📕N-nitroso compounds in the factory environmentDavid P. Rounbehler · 1983
- 📕N-nitroso compoundsInternational Symposium on N-nitroso Compounds (7th 1981 Tokyo, Japan) · 1982
- 📕Some excited and ground state reactions of C-nitroso compoundsJohannes Antonie Maassen · 1972
- 📕N-Nitroso CompoundsH. Bartsch, I.K. O'Neill · 1981
N-nitroso compounds, analysis, formation, and occurrenceInternational Symposium on N-nitroso Compounds (6th 1979 Budapest, Hungary) · 1980- 📕N-nitroso compounds analysis and formationP. Bogovski, E. A. Walker · 1972
Ranked by number of editions on Open Library, a rough measure of how lasting a book is.
đź”— Related topics
- Nitrosamine Nitrosamines (or more formally N-nitrosamines) are organic compounds produced by industrial processes.[better source needed] The chemical structure is…
- Nitrosation and nitrosylation Nitrosation and nitrosylation are two names for the process of converting organic compounds or metal complexes into nitroso derivatives, i.e., compounds…
- Nitrosamine formation during digestion In biochemistry, nitrosamines are a class of compounds that can form during food digestion, or in food processing and preparation. The presence of their…
- Barton nitrite ester reaction The Barton reaction, also known as the Barton nitrite ester reaction, is a photochemical reaction that involves the photolysis of an alkyl nitrite to form…
- Nitrosyl chloride Nitrosyl chloride is the chemical compound with the formula NOCl. It is a yellow gas that is commonly encountered as a component of aqua regia, a mixture…
- Trifluoronitrosomethane Trifluoronitrosomethane (commonly abbreviated as TFNM) is a toxic and unstable gaseous compound consisting of a trifluoromethyl group covalently bound…
- Nitrite The nitrite ion has the chemical formula NO2–. Nitrite (mostly sodium nitrite) is widely used throughout chemical and pharmaceutical industries. The nitrite…
- Dinitrogen trioxide Dinitrogen trioxide (also known as nitrous anhydride) is the inorganic compound with the formula N2O3. It is a nitrogen oxide. It forms upon mixing equal…