Everything about N7

🧭 Start here: a 6-step reading path

1. Read the overview: N7A 5-minute orientation
2. Skim a recent paper: Aberrant translation regulated by METTL1/WDR4‐mediated tRNA N7‐methylguanosine modification drives head and neck squamous cell carcinoma progressionInfluential work since 2022
3. Pick up a classic book: The Great GatsbyThe most-reprinted book on the subject
4. Read the landmark paper: WIDTHS OF THE ATOMIC K–N7 LEVELSCited 740 times
5. Go sideways: N4A closely related topic
6. Go sideways: N9A closely related topic

🏆 Landmark papers (most cited)

• WIDTHS OF THE ATOMIC K–N7 LEVELS

  J.L. CAMPBELL, TIBOR PAPP · 2001 · Atomic Data and Nuclear Data Tables · 740 citations

• Why Does Cisplatin Reach Guanine-N7 with Competing S-Donor Ligands Available in the Cell?

  Jan Reedijk · 1999 · Chemical Reviews · 715 citations

• Transcriptome-wide Mapping of Internal N7-Methylguanosine Methylome in Mammalian mRNA

  Li-Sheng Zhang, Chang Liu, Honghui Ma · 2019 · Molecular Cell · 489 citations

• Functional screen reveals SARS coronavirus nonstructural protein nsp14 as a novel cap N7 methyltransferase

  Yu Chen, Hui Cai, Ji'an Pan · 2009 · Proceedings of the National Academy of Sciences · 441 citations

• Dynamic methylome of internal mRNA N7-methylguanosine and its regulatory role in translation

  Lionel Malbec, Ting Zhang, Yu-Sheng Chen · 2019 · Cell Research · 285 citations

• N7-Methylguanosine tRNA modification enhances oncogenic mRNA translation and promotes intrahepatic cholangiocarcinoma progression

  Zihao Dai, Haining Liu, Junbin Liao · 2021 · Molecular Cell · 273 citations

• The potential role of N7-methylguanosine (m7G) in cancer

  Yuejun Luo, Yuxin Yao, Peng Wu · 2022 · Journal of Hematology & Oncology · 247 citations

• Biologically Relevant Chemical Reactions of N7-Alkylguanine Residues in DNA

  Kent S. Gates, Tony Nooner, Sanjay Dutta · 2004 · Chemical Research in Toxicology · 240 citations

🆕 Influential since 2022

• Aberrant translation regulated by METTL1/WDR4‐mediated tRNA N7‐methylguanosine modification drives head and neck squamous cell carcinoma progression

  Jie Chen, Kang Li, Jianwen Chen · 2022 · Cancer Communications · 190 citations

• N7-methylguanosine tRNA modification promotes esophageal squamous cell carcinoma tumorigenesis via the RPTOR/ULK1/autophagy axis

  Hui Han, Chunlong Yang, Jieyi Ma · 2022 · Nature Communications · 162 citations

• N7-methylguanosine tRNA modification promotes tumorigenesis and chemoresistance through WNT/β-catenin pathway in nasopharyngeal carcinoma

  Binbin Chen, Wei Jiang, Ying Huang · 2022 · Oncogene · 113 citations

• Role of N7-methylguanosine (m7G) in cancer

  Yongping Chen, Huiran Lin, Lei Miao · 2022 · Trends in Cell Biology · 64 citations

• THRONE: A New Approach for Accurate Prediction of Human RNA N7-Methylguanosine Sites

  Watshara Shoombuatong, Shaherin Basith, Thejkiran Pitti · 2022 · Journal of Molecular Biology · 59 citations

📚 Books worth reading

• The Great GatsbyF. Scott Fitzgerald · 1920
• Northanger AbbeyJane Austen · 1818
• Max ErnstMax Ernst, Werner Spies · 1956
• NeuromancerWilliam Gibson · 1984
• Harriet the SpyLouise Fitzhugh · 1960
• From the Mixed-Up Files of Mrs. Basil E. FrankweilerE. L. Konigsburg, Jill Clayburgh · 1967
• The Life of NelsonRobert Southey · 1800
• Publication Manual of the American Psycological AssociationAmerican Psychological Association., American Psychological Association · 1952

Ranked by number of editions on Open Library, a rough measure of how lasting a book is.

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