Everything about MK

🧭 Start here: a 6-step reading path

1. Read the overview: MKA 5-minute orientation
2. Skim a recent paper: Phase 2b Randomized Trial of the Oral PCSK9 Inhibitor MK-0616Influential work since 2022
3. Pick up a classic book: The Government and Politics of the European UnionThe most-reprinted book on the subject
4. Read the landmark paper: The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist.Cited 1,046 times
5. Go sideways: Central Milton KeynesA closely related topic
6. Go sideways: MKOA closely related topic

🏆 Landmark papers (most cited)

• The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist.

  E H Wong, J A Kemp, T Priestley · 1986 · Proceedings of the National Academy of Sciences · 1,046 citations

• Inhibition of Morphine Tolerance and Dependence by the NMDA Receptor Antagonist MK-801

  Keith A. Trujillo, Huda Akil · 1991 · Science · 1,002 citations

• MK-2206, an Allosteric Akt Inhibitor, Enhances Antitumor Efficacy by Standard Chemotherapeutic Agents or Molecular Targeted Drugs In vitro and In vivo

  Hiroshi Hirai, Hiroshi Sootome, Yoko Nakatsuru · 2010 · Molecular Cancer Therapeutics · 861 citations

• Phase I Study of Pembrolizumab (MK-3475; Anti–PD-1 Monoclonal Antibody) in Patients with Advanced Solid Tumors

  Amita Patnaik, S. Peter Kang, Drew Rasco · 2015 · Clinical Cancer Research · 725 citations

• Cooperative Modulation of [3H]MK‐801 Binding to the N‐Methyl‐d‐Aspartate Receptor‐Ion Channel Complex by l‐Glutamate, Glycine, and Polyamines

  Richard W. Ransom, Nancy L. Stec · 1988 · Journal of Neurochemistry · 679 citations

• Block of N-methyl-D-aspartate-activated current by the anticonvulsant MK-801: selective binding to open channels.

  J E Huettner, B P Bean · 1988 · Proceedings of the National Academy of Sciences · 540 citations

• Systemic administration of MK-801 protects against ischemia-induced hippocampal neurodegeneration in the gerbil

  R Gill, AC Foster, GN Woodruff · 1987 · The Journal of Neuroscience · 531 citations

• Small-molecule inhibition of Wee1 kinase by MK-1775 selectively sensitizes p53-deficient tumor cells to DNA-damaging agents

  Hiroshi Hirai, Yoshikazu Iwasawa, Megumu Okada · 2009 · Molecular Cancer Therapeutics · 505 citations

🆕 Influential since 2022

• Phase 2b Randomized Trial of the Oral PCSK9 Inhibitor MK-0616

  Christie M. Ballantyne, Puja Banka, Gustavo Mendez · 2023 · JACC · 226 citations

• Discovery of MK-1454: A Potent Cyclic Dinucleotide Stimulator of Interferon Genes Agonist for the Treatment of Cancer

  Wonsuk Chang, Michael D. Altman, Charles A. Lesburg · 2022 · Journal of Medicinal Chemistry · 156 citations

• Application of MK trend and test of Sen's slope estimator to measure impact of climate change on the adoption of conservation agriculture in Ethiopia

  Han Jiqin, Fikiru Temesgen Gelata, Samerawit Chaka Gemeda · 2023 · Journal of Water and Climate Change · 105 citations

• The influence of calcium hydroxide on the performance of MK-based geopolymer

  Bing Ma, Yang Luo, Lianzhu Zhou · 2022 · Construction and Building Materials · 65 citations

• Synergetic effect of nano-silica fume for enhancing physico-mechanical properties and thermal behavior of MK-geopolymer composites

  H.M. Khater, Mahmoud Gharieb · 2022 · Construction and Building Materials · 62 citations

📚 Books worth reading

• The Government and Politics of the European UnionNeill Nugent · 1994
• 📕Mikalojus Konstantinas ČiurlionisMikalojus Konstantinas Čiurlionis · 1977
• Satan's undergroundLauren Stratford · 1988
• 📕M.K. ČiurlionisMikalojus Konstantinas Čiurlionis · 1961
• M.K. Čiurlionis 1875-1911Mikalojus Konstantinas Čiurlionis · 1979
• 📕Moskovskai︠a︡ vlastʹS. D. Garni︠u︡k · 2012
• 📕Moskovskai︠a︡ partiĭnai︠a︡ organizat︠s︡ii︠a︡ v uslovii︠a︡kh razvitogo sot︠s︡ializmaI. S. Smirnov · 1983
• 📕Mind Controlled Sex Slaves And The CIATracy R. Twymann · 2008

Ranked by number of editions on Open Library, a rough measure of how lasting a book is.

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