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Everything about LRRC26
Protein-coding gene in the species Homo sapiens
Leucine rich repeat containing 26 (LRRC26) is a protein that in humans is encoded by the LRRC26 gene. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: LRRC26A 5-minute orientation
- Skim a recent paper: Tuning the gate and the gear: The LRRC26 (γ1) subunit modulates intrinsic gating and voltage-sensor coupling of the BK channelInfluential work since 2022
- Read the landmark paper: LRRC26 auxiliary protein allows BK channel activation at resting voltage without calciumCited 236 times
- Go sideways: LGR6A closely related topic
- Go sideways: NLRC4A closely related topic
📖 Definitions
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🗂️ The subject at a glance
No outline available.
🏆 Landmark papers (most cited)
LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium
LRRC26 Is a Functional BK Channel Auxiliary γ Subunit in Arterial Smooth Muscle Cells
The LRRC26 Protein Selectively Alters the Efficacy of BK Channel Activators
Knockout of the LRRC26 subunit reveals a primary role of LRRC26-containing BK channels in secretory epithelial cells
Goblet cell LRRC26 regulates BK channel activation and protects against colitis in mice
Roles of LRRC26 as an auxiliary γ1-subunit of large-conductance Ca 2+ -activated K + channels in bronchial smooth muscle cells
A new “opening” act on the BK channel stage: Identification of LRRC26 as a novel BK channel accessory subunit that enhances voltage-dependent gating
Frequent downregulation of LRRC26 by epigenetic alterations is involved in the malignant progression of triple-negative breast cancer
🆕 Influential since 2022
Tuning the gate and the gear: The LRRC26 (γ1) subunit modulates intrinsic gating and voltage-sensor coupling of the BK channel
BPS2025 - Gating and ionic currents reveal how the LRRC26 (γ1) subunit modulates the BK channel gating
Concatenated modular BK channel constructs reveal divergent stoichiometry in gating control by LRRC26 (γ1), pore, and selectivity filter
Transgenic Expression of BK Channel Auxiliary LRRC26 Subunit in the Forebrain Causes Locomotor Hyperactivity and Cognitive Defects
BPS2026 – LRRC26-associated BK channels regulate membrane potential and intracellular calcium signaling in colonic goblet cells
📚 Books worth reading
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🔗 Related topics
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