Everything about Ko

🧭 Start here: a 6-step reading path

1. Read the overview: KoA 5-minute orientation
2. Skim a recent paper: Activity of menin inhibitor ziftomenib (KO-539) as monotherapy or in combinations against AML cells with MLL1 rearrangement or mutant NPM1Influential work since 2022
3. Pick up a classic book: Ungeduld des HerzensThe most-reprinted book on the subject
4. Read the landmark paper: Automated genome annotation and pathway identification using the KEGG Orthology (KO) as a controlled vocabularyCited 3,337 times
5. Go sideways: JiA closely related topic
6. Go sideways: KEA closely related topic

🏆 Landmark papers (most cited)

• Automated genome annotation and pathway identification using the KEGG Orthology (KO) as a controlled vocabulary

  X. Mao, T. Cai, J. G. Olyarchuk · 2005 · Bioinformatics · 3,337 citations

• KO t Bu: A Privileged Reagent for Electron Transfer Reactions?

  Joshua P. Barham, Graeme Coulthard, Katie J. Emery · 2016 · Journal of the American Chemical Society · 338 citations

• Generation of APLP2 KO Mice and Early Postnatal Lethality in APLP2/APP Double KO Mice

  C.S. von Koch, H. Zheng, H. Chen · 1997 · Neurobiology of Aging · 281 citations

• Rescue of behavioral phenotype and neuronal protrusion morphology in Fmr1 KO mice

  Femke M.S. de Vrij, Josien Levenga, Herma C. van der Linde · 2008 · Neurobiology of Disease · 278 citations

• Impairment of synaptic plasticity and memory formation in GLP-1 receptor KO mice: Interaction between type 2 diabetes and Alzheimer's disease

  Talib Abbas, Emilie Faivre, Christian Hölscher · 2009 · Behavioural Brain Research · 244 citations

• Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by the small-molecule PAK inhibitor FRAX486

  Bridget M. Dolan, Sergio G. Duron, David A. Campbell · 2013 · Proceedings of the National Academy of Sciences · 222 citations

• The exact bound in the Erdös-Ko-Rado theorem

  Richard M. Wilson · 1984 · Combinatorica · 215 citations

• Modifying behavioral phenotypes in Fmr1KO mice: genetic background differences reveal autistic‐like responses

  Corinne M. Spencer, Olga Alekseyenko, Shannon M. Hamilton · 2011 · Autism Research · 201 citations

🆕 Influential since 2022

• Activity of menin inhibitor ziftomenib (KO-539) as monotherapy or in combinations against AML cells with MLL1 rearrangement or mutant NPM1

  Warren Fiskus, Naval Daver, Steffen Boettcher · 2022 · Leukemia · 80 citations

• Update on a Phase 1/2 First-in-Human Study of the Menin-KMT2A (MLL) Inhibitor Ziftomenib (KO-539) in Patients with Relapsed or Refractory Acute Myeloid Leukemia

  Harry P. Erba, Amir T. Fathi, Ghayas C. Issa · 2022 · Blood · 69 citations

• Leukocytes mediate disease pathogenesis in the Ndufs4(KO) mouse model of Leigh syndrome

  Julia C. Stokes, Rebecca L. Bornstein, Katerina James · 2022 · JCI Insight · 63 citations

• Alteration of Gut Microbiome and Correlated Amino Acid Metabolism Contribute to Hyperuricemia and Th17-Driven Inflammation in Uox-KO Mice

  Siyue Song, Yu Lou, Yingying Mao · 2022 · Frontiers in Immunology · 59 citations

• Menin inhibitor ziftomenib (KO-539) synergizes with drugs targeting chromatin regulation or apoptosis and sensitizes acute myeloid leukemia with <i>MLL</i> rearrangement or <i>NPM1</i> mutation to venetoclax

  Johanna Rausch, Margarita M. Dzama, Nadezda Dolgikh · 2023 · Haematologica · 52 citations

📚 Books worth reading

• Ungeduld des HerzensStefan Zweig · 1927
• Handbook of contraception and sexual healthSuzanne Everett · 2014
• Your inner fishNeil Shubin · 2008
• Accounting principlesRoger H. Hermanson · 1980
• Gender In World PerspectiveR. W. Connell, Rebecca Pearse · 2009
• Sexy Bodies. Eine soziologische Reise durch den GeschlechtskörperPaula-Irene Villa Braslavsky · 2001
• Bodily communicationMichael Argyle · 1975
• Body LanguageJulius Fast · 1975

Ranked by number of editions on Open Library, a rough measure of how lasting a book is.

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