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Everything about Inversin
Protein found in humans
Inversin, also called Nephrocystin-2, is a protein that in humans is encoded by the INVS gene. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: InversinA 5-minute orientation
- Skim a recent paper: PCP Protein Inversin Regulates Testis Function Through Changes in Cytoskeletal Organization of Actin and MicrotubulesInfluential work since 2022
- Pick up a classic book: Micro-hydropower sourcebookThe most-reprinted book on the subject
- Read the landmark paper: Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathwaysCited 687 times
- Go sideways: Nephrocystin-4A closely related topic
- Go sideways: Nephrocystin-3A closely related topic
📖 Definitions
Noun A ciliary protein that is required for normal renal development
🗂️ The subject at a glance
🏆 Landmark papers (most cited)
Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways
Mutations in INVS encoding inversin cause nephronophthisis type 2, linking renal cystic disease to the function of primary cilia and left-right axis determination
Inversin, a novel gene in the vertebrate left-right axis pathway, is partially deleted in the inv mouse
The left-right determinant Inversin is a component of node monocilia and other 9+0 cilia
Expression analyses and interaction with the anaphase promoting complex protein Apc2 suggest a role for inversin in primary cilia and involvement in the cell cycle
Inversin Forms a Complex with Catenins and N-Cadherin in Polarized Epithelial Cells
Inversin, Wnt signaling and primary cilia
Inversin/Nephrocystin-2 Is Required for Fibroblast Polarity and Directional Cell Migration
🆕 Influential since 2022
PCP Protein Inversin Regulates Testis Function Through Changes in Cytoskeletal Organization of Actin and Microtubules
Dimerization activates the Inversin complex in C. elegans
Identifying an Inversin as a Novel Prognostic Marker in Patients with Clear-Cell Renal Cell Carcinoma
Inversin (NPHP2) and Vangl2 are required for normal zebrafish cloaca formation
Case Report: Adolescent-Onset Isolated Nephronophthisis Caused by a Novel Homozygous Inversin Mutation
📚 Books worth reading
Micro-hydropower sourcebookAllen R. Inversin · 1986- 📕Hydraulic RamAllen Inversin · 1979
Phǣng mǣ =ʻUthin Bunnyāvong., ʻUthin Bunnyāvong · 1991
DE LA INVERSI�N
DE LA INVERSI�N
DE LA INVERSI�N
DE LA INVERSI�N · 2017- 📕Siguiente Nivel de Inversi�n en CriptomonedasWayne Walker · 2018
Ranked by number of editions on Open Library, a rough measure of how lasting a book is.
🔗 Related topics
- Nephrocystin-4 Nephrocystin-4 is a protein that in humans is encoded by the NPHP4 gene. This gene encodes a protein which contains a proline-rich region. The encoded…
- Nephrocystin-3 Nephrocystin-3 is a protein that in humans is encoded by the NPHP3 gene. This gene encodes a protein containing a coiled-coil (CC) domain, a tubulin-tyrosine…
- Nephrocystin-1 Nephrocystin-1 is a protein that in humans is encoded by the NPHP1 gene (previously NPH1). This gene encodes a protein with src homology domain 3 (SH3)…
- IQCB1 IQ calmodulin-binding motif-containing protein 1 is a protein that in humans is encoded by the IQCB1 gene. This protein is involved in early cilia formation…
- Conorenal syndrome Conorenal syndrome is a collection of medical conditions that seem to have a common genetic cause. The exact gene loci has not been characterized. NPHP3:…
- Meckelin Meckelin is a protein that in humans is encoded by the TMEM67 gene. The protein encoded by this gene localizes to the primary cilium and to the plasma…
- NEK8 Serine/threonine-protein kinase Nek8, also known as never in mitosis A-related kinase 8, is an enzyme that in humans is encoded by the NEK8 gene. Nek8…
- BBS2 Bardet–Biedl syndrome 2 protein is a protein that in humans is encoded by the BBS2 gene. This gene encodes a protein of unknown function. Mutations in…