Everything about H3 Podcast

🧭 Start here: a 6-step reading path

1. Read the overview: H3 PodcastA 5-minute orientation
2. Skim a recent paper: Tumor-derived lactate promotes resistance to bevacizumab treatment by facilitating autophagy enhancer protein RUBCNL expression through histone H3 lysine 18 lactylation (H3K18la) in colorectal cancerInfluential work since 2022
3. Pick up a classic book: Il purgatorioThe most-reprinted book on the subject
4. Read the landmark paper: Role of Histone H3 Lysine 27 Methylation in Polycomb-Group SilencingCited 3,466 times
5. Go sideways: H3h3ProductionsA closely related topic
6. Go sideways: Leftovers (podcast)A closely related topic

🏆 Landmark papers (most cited)

• Role of Histone H3 Lysine 27 Methylation in Polycomb-Group Silencing

  Ru Cao, Liangjun Wang, Hengbin Wang · 2002 · Science · 3,466 citations

• Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain

  Andrew J. Bannister, Philip Zegerman, Janet F. Partridge · 2001 · Nature · 2,625 citations

• Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins

  Monika Lachner, Dónal O'Carroll, Stephen Rea · 2001 · Nature · 2,565 citations

• Regulation of chromatin structure by site-specific histone H3 methyltransferases

  Stephen Rea, Frank Eisenhaber, Dónal O'Carroll · 2000 · Nature · 2,520 citations

• Active genes are tri-methylated at K4 of histone H3

  Helena Santos-Rosa, Robert Schneider, Andrew J. Bannister · 2002 · Nature · 1,911 citations

• Regulation of Heterochromatic Silencing and Histone H3 Lysine-9 Methylation by RNAi

  Thomas A. Volpe, Catherine Kidner, Ira M. Hall · 2002 · Science · 1,783 citations

• Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation

  Michael J. Hendzel, Yi Wei, Michael A. Mancini · 1997 · Chromosoma · 1,670 citations

• Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas

  St. Jude Children's Research Hospital–Washington University Pediatric Cancer Genome Project · 2012 · Nature Genetics · 1,614 citations

🆕 Influential since 2022

• Tumor-derived lactate promotes resistance to bevacizumab treatment by facilitating autophagy enhancer protein RUBCNL expression through histone H3 lysine 18 lactylation (H3K18la) in colorectal cancer

  Weihao Li, Chi Zhou, Long Yu · 2023 · Autophagy · 489 citations

• Intraventricular B7-H3 CAR T Cells for Diffuse Intrinsic Pontine Glioma: Preliminary First-in-Human Bioactivity and Safety

  Nicholas A. Vitanza, Ashley L. Wilson, Wenjun Huang · 2022 · Cancer Discovery · 282 citations

• New frontiers in immune checkpoint B7-H3 (CD276) research and drug development

  Ayechew Adera Getu, Abiye Tigabu, Ming Zhou · 2023 · Molecular Cancer · 263 citations

• The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location

  Ilon Liu, Li Jiang, Erik R. Samuelsson · 2022 · Nature Genetics · 227 citations

• Immune checkpoint of B7-H3 in cancer: from immunology to clinical immunotherapy

  Binghao Zhao, Huanzhang Li, Yu Xia · 2022 · Journal of Hematology & Oncology · 208 citations

📚 Books worth reading

• Il purgatorioDante Alighieri · 1768
• John Donne PoetryJohn Donne, John Booty · 1633
• HippolytusEuripides, Euripides · 1756
• The Haunting of Hill HouseShirley Jackson · 1959
• Caligula, suivi de Le malentenduAlbert Camus · 1900
• Biedermann und die BrandstifterMax Frisch · 1958
• A mathematician's apologyG. H. Hardy, Iñaki Iñurrieta Labaien · 1940
• Religions of the worldLewis M. Hopfe, Mark R. Woodward · 1976

Ranked by number of editions on Open Library, a rough measure of how lasting a book is.

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