Everything about Fat

🧭 Start here: a 6-step reading path

1. Read the overview: FatA 5-minute orientation
2. Skim a recent paper: Pathogenesis of sarcopenia and the relationship with fat mass: descriptive reviewInfluential work since 2022
3. Pick up a classic book: Hustler (Alpha Books)The most-reprinted book on the subject
4. Read the landmark paper: Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistanceCited 6,945 times
5. Go sideways: Saturated fatA closely related topic
6. Go sideways: Monounsaturated fatA closely related topic

🏆 Landmark papers (most cited)

• Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

  Haiyan Xu, Glenn T. Barnes, Qing Yang · 2003 · Journal of Clinical Investigation · 6,945 citations

• The gut microbiota as an environmental factor that regulates fat storage

  Fredrik Bäckhed, Hao Ding, Ting Wang · 2004 · Proceedings of the National Academy of Sciences · 5,475 citations

• Body fat assessed from total body density and its estimation from skinfold thickness: measurements on 481 men and women aged from 16 to 72 Years

  J. V. G. A. Durnin, J. Womersley · 1974 · British Journal of Nutrition · 4,558 citations

• Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet–Induced Obesity and Diabetes in Mice

  Patrice D. Cani, Rodrigo Bibiloni, Claude Knauf · 2008 · Diabetes · 4,396 citations

• A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis

  Pontus Boström, Jun Wu, Mark P. Jedrychowski · 2012 · Nature · 4,348 citations

• The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

  T. Yamauchi, J. Kamon, H. Waki · 2001 · Nature Medicine · 3,948 citations

• Metabolism of Isolated Fat Cells

  Martin Rodbell · 1964 · Journal of Biological Chemistry · 3,478 citations

• Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human

  Jun Wu, Pontus Boström, Lauren M. Sparks · 2012 · Cell · 3,131 citations

🆕 Influential since 2022

• Pathogenesis of sarcopenia and the relationship with fat mass: descriptive review

  Chun‐wei Li, Kang Yu, Ng Shyh‐Chang · 2022 · Journal of Cachexia, Sarcopenia and Muscle · 621 citations

• Long-term secondary prevention of cardiovascular disease with a Mediterranean diet and a low-fat diet (CORDIOPREV): a randomised controlled trial

  Javier Delgado-Lista, Juan F Alcala-Diaz, Jose D Torres-Peña · 2022 · The Lancet · 618 citations

• FAT-Net: Feature adaptive transformers for automated skin lesion segmentation

  Huisi Wu, Shihuai Chen, Guilian Chen · 2022 · Medical Image Analysis · 584 citations

• High-Fat Diet Promotes Colorectal Tumorigenesis Through Modulating Gut Microbiota and Metabolites

  Jia Yang, Hong Wei, Yunfei Zhou · 2022 · Gastroenterology · 504 citations

• Effect of tirzepatide versus insulin degludec on liver fat content and abdominal adipose tissue in people with type 2 diabetes (SURPASS-3 MRI): a substudy of the randomised, open-label, parallel-group, phase 3 SURPASS-3 trial

  Amalia Gastaldelli, Kenneth Cusi, Laura Fernández Landó · 2022 · The Lancet Diabetes & Endocrinology · 498 citations

📚 Books worth reading

• Hustler (Alpha Books)Walter S. Tevis · 1959
• Fats and OilsRichard D. O'Brien · 1997
• In the kitchen with RosieRosie Daley · 1994
• VeganomiconIsa Chandra Moskowitz, Terry Hope Romero · 2007
• The story of CriscoMarion Harris Neil · 1914
• Industrial oil and fat productsAlton Edward Bailey · 1945
• Salt Sugar FatMichael Moss · 2013
• The T-Factor DietMartin Katahn · 1989

Ranked by number of editions on Open Library, a rough measure of how lasting a book is.

🔗 Related topics

• Saturated fat A saturated fat is a type of fat: a glyceride in which the fatty acid chains have all single bonds between the carbon atoms. Glyceride fats with single…
• Monounsaturated fat In biochemistry and nutrition, a monounsaturated fat is a fat which contains a monounsaturated fatty acid (MUFA), a subclass of fatty acid characterized…
• Trans fat Trans fat is a type of unsaturated fat that occurs in foods. Trans fats are fats (triglycerides, i.e. triple esters of glycerin) that contain chains derived…
• Palmitic acid Palmitic acid (hexadecanoic acid in IUPAC nomenclature) is a fatty acid with a 16-carbon chain. It is the most common saturated fatty acid found in animals…
• Omega−6 fatty acid Omega−6 fatty acids (also referred to as ω−6 fatty acids or n−6 fatty acids) are a family of essential polyunsaturated fatty acids (PUFA) that share a…
• Low-fat diet A low-fat diet is one that restricts fat, and often saturated fat and cholesterol as well. Low-fat diets are intended to reduce the occurrence of conditions…
• Cooking oil Cooking oil (also known as edible oil) is a plant or animal liquid fat used in frying, baking, and other types of cooking. Oil allows higher cooking temperature…
• Polyunsaturated fat In biochemistry and nutrition, a polyunsaturated fat is a fat that contains a polyunsaturated fatty acid (abbreviated PUFA), which is a subclass of fatty…