Everything about Daf

🧭 Start here: a 6-step reading path

1. Read the overview: DafA 5-minute orientation
2. Skim a recent paper: Intestine-specific removal of DAF-2 nearly doubles lifespan in Caenorhabditis elegans with little fitness costInfluential work since 2022
3. Pick up a classic book: Idols of ISISThe most-reprinted book on the subject
4. Read the landmark paper: Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegansCited 2,029 times
5. Go sideways: TambourineA closely related topic
6. Go sideways: List of Indian musical instrumentsA closely related topic

🏆 Landmark papers (most cited)

• Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans

  Coleen T. Murphy, Steven A. McCarroll, Cornelia I. Bargmann · 2003 · Nature · 2,029 citations

• daf-2 , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in Caenorhabditis elegans

  Koutarou D. Kimura, Heidi A. Tissenbaum, Yanxia Liu · 1997 · Science · 1,939 citations

• The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

  Scott Ogg, Suzanne Paradis, Shoshanna Gottlieb · 1997 · Nature · 1,671 citations

• Regulation of Aging and Age-Related Disease by DAF-16 and Heat-Shock Factor

  Ao-Lin Hsu, Coleen T. Murphy, Cynthia Kenyon · 2003 · Science · 1,369 citations

• daf-16 : An HNF-3/forkhead Family Member That Can Function to Double the Life-Span of Caenorhabditis elegans

  Kui Lin, Jennie B. Dorman, Aylin Rodan · 1997 · Science · 1,316 citations

• Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling

  Kui Lin, Honor Hsin, Natasha Libina · 2001 · Nature Genetics · 917 citations

• daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans

  Samuel T. Henderson, Thomas E. Johnson · 2001 · Current Biology · 817 citations

• Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues

  Tatsuo FURUYAMA, Toru NAKAZAWA, Itsuko NAKANO · 2000 · Biochemical Journal · 789 citations

🆕 Influential since 2022

• Intestine-specific removal of DAF-2 nearly doubles lifespan in Caenorhabditis elegans with little fitness cost

  Yan-Ping Zhang, Wen-Hong Zhang, Pan Zhang · 2022 · Nature Communications · 94 citations

• Strawberry (Fragaria × ananassa cv. Romina) methanolic extract attenuates Alzheimer’s beta amyloid production and oxidative stress by SKN-1/NRF and DAF-16/FOXO mediated mechanisms in C. elegans

  María D. Navarro-Hortal, Jose M. Romero-Márquez, Adelaida Esteban-Muñoz · 2022 · Food Chemistry · 87 citations

• Lentinan extends lifespan and increases oxidative stress resistance through DAF-16 and SKN-1 pathways in Caenorhabditis elegans

  Huimin Liu, Ying Wang, Weiping Zhang · 2022 · International Journal of Biological Macromolecules · 61 citations

• DAF‐2/insulin IGF‐1 receptor regulates motility during aging by integrating opposite signaling from muscle and neuronal tissues

  Charline Roy, Laurent Molin, Allan Alcolei · 2022 · Aging Cell · 50 citations

• Bacillus coagulans (Weizmannia coagulans) XY2 attenuates Cu-induced oxidative stress via DAF-16/FoxO and SKN-1/Nrf2 pathways and gut microbiota regulation

  Yufang Gao, Ting Yu, Yalan Wu · 2023 · Journal of Hazardous Materials · 48 citations

📚 Books worth reading

• 📕Idols of ISISAaron Tugendhaft · 2020
• 📕לקט מכתבי תודהMosdot irgun ha-daf ha-yomi ha-ʻolami
• DAF 55, 66, 66-1300 1967-74 Autobook ...Kenneth Ball · 1974
• 📕DAFEric Gibbins · 1981
• 📕DafPat Kennett · 1979
• 📕Repair guide, DAF 55 ..Peter Russek · 1973
• DAF 55, 66 1967-75 Autobook ...Kenneth Ball · 1976
• Rede zum ReichsparteitagRobert Ley · 1934

Ranked by number of editions on Open Library, a rough measure of how lasting a book is.

🔗 Related topics

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