Everything about D2L

🧭 Start here: a 6-step reading path

1. Read the overview: D2LA 5-minute orientation
2. Skim a recent paper: Allosteric modulation of dopamine D2L receptor in complex with Gi1 and Gi2 proteins: the effect of subtle structural and stereochemical ligand modificationsInfluential work since 2022
3. Pick up a classic book: Ab urbe conditaThe most-reprinted book on the subject
4. Read the landmark paper: Distinct roles of dopamine D2L and D2S receptor isoforms in the regulation of protein phosphorylation at presynaptic and postsynaptic sitesCited 168 times
5. Go sideways: EdsbyA closely related topic
6. Go sideways: Learning Tools InteroperabilityA closely related topic

🏆 Landmark papers (most cited)

• Distinct roles of dopamine D2L and D2S receptor isoforms in the regulation of protein phosphorylation at presynaptic and postsynaptic sites

  Niklas Lindgren, Alessandro Usiello, Michel Goiny · 2003 · Proceedings of the National Academy of Sciences · 168 citations

• Human Dopamine D3 and D2L Receptors Couple to Inward Rectifier Potassium Channels in Mammalian Cell Lines

  Eldo V. Kuzhikandathil, Weifeng Yu, Gerry S. Oxford · 1998 · Molecular and Cellular Neuroscience · 97 citations

• Dopamine D2L receptor knockout mice display deficits in positive and negative reinforcing properties of morphine and in avoidance learning

  J.W Smith, L.A Fetsko, R Xu · 2002 · Neuroscience · 91 citations

• D2 Dopamine Receptors Stimulate Mitogenesis Through Pertussis Toxin‐Sensitive G Proteins and Ras‐Involved ERK and SAP/JNK Pathways in Rat C6‐D2L Glioma Cells

  Yongquan Luo, Gertrude C. Kokkonen, Xiantao Wang · 1998 · Journal of Neurochemistry · 91 citations

• Chronic Haloperidol Promotes Corticostriatal Long-Term Potentiation by Targeting Dopamine D2L Receptors

  Diego Centonze, Alessandro Usiello, Cinzia Costa · 2004 · The Journal of Neuroscience · 85 citations

• Differential contribution of dopamine D2S and D2L receptors in the modulation of glutamate and GABA transmission in the striatum

  D. Centonze, P. Gubellini, A. Usiello · 2004 · Neuroscience · 81 citations

• Dopamine D2 Receptor-Mediated Inhibition of Dopaminergic Neurons in Mice Lacking D2L Receptors

  D Centonze · 2002 · Neuropsychopharmacology · 78 citations

• Aripiprazole's low intrinsic activities at human dopamine D2L and D2S receptors render it a unique antipsychotic

  Yoshihiro Tadori, Takashi Miwa, Katsura Tottori · 2005 · European Journal of Pharmacology · 74 citations

🆕 Influential since 2022

• Allosteric modulation of dopamine D2L receptor in complex with Gi1 and Gi2 proteins: the effect of subtle structural and stereochemical ligand modifications

  Justyna Żuk, Damian Bartuzi, Andrea G. Silva · 2022 · Pharmacological Reports · 6 citations

• Dopamine D2S/D2L Receptor Regulation of Alcohol‐Induced Reward and Signalling

  Mohd Tayyab, Toshikuni Sasaoka, Manabu Abe · 2025 · Addiction Biology · 3 citations

• Dopamine D2L Receptor Deficiency Alters Neuronal Excitability and Spine Formation in Mouse Striatum

  Gubbi Govindaiah, Rong-Jian Liu, Yanyan Wang · 2022 · Biomedicines · 3 citations

• Dopamine D2L receptor density influences the recruitment of β-arrestin2 and Gi1 induced by antiparkinsonian drugs

  Mattia Ferraiolo, Hicham Atik, Romane Ponthot · 2022 · Neuropharmacology · 2 citations

• فاعلية استراتيجية تدريسية تستند إلى نظام D2L للتعلّم الإلكتروني في تنمية مهارتي الإحساس بالمشكلة والتعلم الذاتي لدى الطلاب المعلمين تخصص الفيزياء في جامعة المجمعة

  عبد الله الحربي · 2022 · مجلة جامعة الشارقة للعلوم الانسانية والاجتماعية · 1 citations

📚 Books worth reading

• Ab urbe conditaTitus Livius · 1481
• LolitaVladimir Nabokov · 1777
• Maus IArt Spiegelman · 1986
• No Place to HideGlenn Greenwald · 2013
• Totémisme aujourd'huiClaude Lévi-Strauss · 1963
• Cradle to CradleWilliam McDonough, Michael Braungart · 2002
• How to change the worldDavid Bornstein · 2003
• WikinomicsDon Tapscott, Anthony D. Williams · 2006

Ranked by number of editions on Open Library, a rough measure of how lasting a book is.

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