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Everything about Coagulation
Process of formation of blood clots
Coagulation, also known as clotting, is the process by which blood changes from a liquid to a gel forming a blood clot. The process involves activation, adhesion and aggregation of platelets, as well as deposition and maturation of fibrin. Coagulation results in hemostasis, the cessation of blood loss from a damaged vessel, allowing repair. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: CoagulationA 5-minute orientation
- Skim a recent paper: Removal of methylene blue (basic dye) by coagulation-flocculation with biomaterials (bentonite and Opuntia ficus indica)Influential work since 2022
- Pick up a classic book: Sang et Son Troisième Élément Anatomique ... ...The most-reprinted book on the subject
- Read the landmark paper: Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumoniaCited 4,663 times
- Go sideways: ThrombinA closely related topic
- Go sideways: Disseminated intravascular coagulationA closely related topic
📖 Definitions
Noun The precipitation of suspended particles as they increase in size by any of several physical or chemical processes.
Noun The process by which blood forms solid clots.
Noun Similar solidification of other materials (e.g. of tofu).
🗂️ The subject at a glance
🏆 Landmark papers (most cited)
Abnormal coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia
Mutation in blood coagulation factor V associated with resistance to activated protein C
Towards Definition, Clinical and Laboratory Criteria, and a Scoring System for Disseminated Intravascular Coagulation
Mutual coagulation of colloidal dispersions
A review on chemical coagulation/flocculation technologies for removal of colour from textile wastewaters
The coagulation cascade: initiation, maintenance, and regulation
Coagulation by hydrolysing metal salts
Inflammatory and Coagulation Biomarkers and Mortality in Patients with HIV Infection
🆕 Influential since 2022
Removal of methylene blue (basic dye) by coagulation-flocculation with biomaterials (bentonite and Opuntia ficus indica)
Recent advancement in the application of hybrid coagulants in coagulation-flocculation of wastewater: A review
Long COVID: pathophysiological factors and abnormalities of coagulation
Surface-functionalized design of blood-contacting biomaterials for preventing coagulation and promoting hemostasis
The removal of microplastics from water by coagulation: A comprehensive review
📚 Books worth reading
Sang et Son Troisième Élément Anatomique ... ...Antoine Béchamp, Montague R. Leverson · 1911
Practical Hemostasis and ThrombosisMichael Makris · 2007
Essential guide to blood coagulationJovan P. Antovic, Margareta Blombäck · 2010
Inherited bleeding disorders in womenChristine A. Lee · 2009
Hemostasis and thrombosisThomas G. DeLoughery · 1999
Disseminated intravascular coagulation and related syndromesRodger L. Bick · 1983
Fibrinolysis in Disease - The Malignant Process, Interventions in Thrombogenic Mechanisms, and Novel Treatment Modalities, Volume 2Pia Glas-Greenwalt · 1995
Human blood coagulation and its disordersRosemary Biggs · 1953
Ranked by number of editions on Open Library, a rough measure of how lasting a book is.
🔗 Related topics
- Thrombin Thrombin (factor IIa, EC 3.4.21.5) is a serine protease that converts fibrinogen into strands of insoluble fibrin, as well as catalyzing many other coagulation-…
- Disseminated intravascular coagulation Disseminated intravascular coagulation (DIC) is a condition in which blood clots form throughout the body, blocking small blood vessels. Symptoms may include…
- Fibrinogen Fibrinogen (coagulation factor I) is a glycoprotein complex, produced in the liver, that circulates in the blood of all vertebrates. During tissue and…
- Coagulation testing Blood clotting tests are the tests used for diagnostics of the hemostasis system. Coagulometer is the medical laboratory analyzer used for testing of the…
- Platelet plug The platelet plug, also known as the hemostatic plug or platelet thrombus, is an aggregation of platelets formed during early stages of hemostasis in response…
- Thrombin time The thrombin time (TT), also known as the thrombin clotting time (TCT), is a blood test that measures the time it takes for a clot to form in the plasma…
- Factor X Coagulation factor X (EC 3.4.21.6), or Stuart factor, is an enzyme of the coagulation cascade, encoded in humans by F10 gene. It is a serine endopeptidase…
- Hypoprothrombinemia Hypoprothrombinemia is a rare blood disorder in which a deficiency in immunoreactive prothrombin (Factor II), produced in the liver, results in an impaired…