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Everything about Cell encapsulation

Cell encapsulation is a possible solution to graft rejection in tissue engineering applications. Cell microencapsulation technology involves immobilization of cells within a polymeric semi-permeable membrane. It permits the bidirectional diffusion of molecules such as the influx of oxygen, nutrients, growth factors etc. essential for cell metabolism and the outward diffusion of waste products and therapeutic proteins. At the same time, the semi-permeable nature of the membrane prevents immune cells and antibodies from destroying the encapsulated cells, regarding them as foreign invaders. On the other hand, single-cell nanoencapsulation (SCNE) involves the formation of nanometric shells around individual living cells. Wikipedia →

🧭 Start here: a 6-step reading path

  1. Read the overview: Cell encapsulationA 5-minute orientation
  2. Skim a recent paper: Cell‐Mediated Biointerfacial Phenolic Assembly for Probiotic Nano EncapsulationInfluential work since 2022
  3. Pick up a classic book: New technologies for bioartificial organsThe most-reprinted book on the subject
  4. Read the landmark paper: Monodisperse Alginate Hydrogel Microbeads for Cell EncapsulationCited 579 times
  5. Go sideways: Micro-encapsulationA closely related topic
  6. Go sideways: Foreign body reactionA closely related topic

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