Everything about Cerebrospinal fluid

🧭 Start here: a 6-step reading path

1. Read the overview: Cerebrospinal fluidA 5-minute orientation
2. Skim a recent paper: GM-CSF: A Double-Edged Sword in Cancer ImmunotherapyInfluential work since 2022
3. Pick up a classic book: British Aerospace plc and Thomson-CSF SAThe most-reprinted book on the subject
4. Read the landmark paper: A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid βCited 5,707 times
5. Go sideways: Ventricular systemA closely related topic
6. Go sideways: Lumbar punctureA closely related topic

🏆 Landmark papers (most cited)

• A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid β

  Jeffrey J. Iliff, Minghuan Wang, Yonghong Liao · 2012 · Science Translational Medicine · 5,707 citations

• A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation

  Gray Shaw, Robert Kamen · 1986 · Cell · 2,952 citations

• CSF-1R inhibition alters macrophage polarization and blocks glioma progression

  Stephanie M Pyonteck, Leila Akkari, Alberto J Schuhmacher · 2013 · Nature Medicine · 2,314 citations

• CSF and blood biomarkers for the diagnosis of Alzheimer's disease: a systematic review and meta-analysis

  Bob Olsson, Ronald Lautner, Ulf Andreasson · 2016 · The Lancet Neurology · 1,893 citations

• Anti-GD2 Antibody with GM-CSF, Interleukin-2, and Isotretinoin for Neuroblastoma

  Alice L. Yu, Andrew L. Gilman, M. Fevzi Ozkaynak · 2010 · New England Journal of Medicine · 1,693 citations

• Targeting Tumor-Associated Macrophages with Anti-CSF-1R Antibody Reveals a Strategy for Cancer Therapy

  Carola H. Ries, Michael A. Cannarile, Sabine Hoves · 2014 · Cancer Cell · 1,298 citations

• Cerebral Arterial Pulsation Drives Paravascular CSF–Interstitial Fluid Exchange in the Murine Brain

  Jeffrey J. Iliff, Minghuan Wang, Douglas M. Zeppenfeld · 2013 · The Journal of Neuroscience · 1,296 citations

• Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF

  Martin Guilliams, Ismé De Kleer, Sandrine Henri · 2013 · Journal of Experimental Medicine · 1,291 citations

🆕 Influential since 2022

• GM-CSF: A Double-Edged Sword in Cancer Immunotherapy

  Anil Kumar, Adeleh Taghi Khani, Ashly Sanchez Ortiz · 2022 · Frontiers in Immunology · 270 citations

• CSF MTBR-tau243 is a specific biomarker of tau tangle pathology in Alzheimer’s disease

  Kanta Horie, Gemma Salvadó, Nicolas R. Barthélemy · 2023 · Nature Medicine · 239 citations

• Plasma and CSF biomarkers in a memory clinic: Head‐to‐head comparison of phosphorylated tau immunoassays

  Nicholas J. Ashton, Albert Puig‐Pijoan, Marta Milà‐Alomà · 2022 · Alzheimer's & Dementia · 227 citations

• Young CSF restores oligodendrogenesis and memory in aged mice via Fgf17

  Tal Iram, Fabian Kern, Achint Kaur · 2022 · Nature · 202 citations

• Soluble TREM2 in CSF and its association with other biomarkers and cognition in autosomal-dominant Alzheimer's disease: a longitudinal observational study

  Estrella Morenas-Rodríguez, Yan Li, Brigitte Nuscher · 2022 · The Lancet Neurology · 171 citations

📚 Books worth reading

• 📕British Aerospace plc and Thomson-CSF SAMonopolies and Mergers Commission · 1991
• The Molecular Basis of Cellular Defence Mechanisms - Symposium No. 204CIBA Foundation Symposium · 1997
• Jean-Luc Lagardère corsaire de la RépubliqueThierry Gadault · 2003
• 📕Les GENS DE LA RADIO - 50 ans d'histoire sociale à Thomson-CSF de CholetInter-Ce Thomson-M. C. · 1997
• L' entreprise partagéeR. Thomas · 1999
• 📕Vers le IIème siécleGaël Boudaud · 1996
• Pending transactions under the Exon-Florio amendmentUnited States. Congress. Senate. Committee on Commerce, Science, and Transportation. · 1992
• Hemopoietic growth factors and mononuclear phagocytesRalph van Furth · 1993

Ranked by number of editions on Open Library, a rough measure of how lasting a book is.

🔗 Related topics

• Ventricular system In neuroanatomy, the ventricular system is a set of four interconnected cavities known as cerebral ventricles in the brain. Within each ventricle is a…
• Lumbar puncture Lumbar puncture (LP), also known as a spinal tap, is a medical procedure in which a needle is inserted into the spinal canal, most commonly to collect…
• Pia mater Pia mater (/ˈpaɪ.ə ˈmeɪtər/ or /ˈpiːə ˈmɑːtər/), often referred to as simply the pia, is the delicate innermost layer of the meninges, the membranes surrounding…
• Arachnoid mater The arachnoid mater (or simply arachnoid) is one of the three meninges, the protective membranes that cover the brain and spinal cord. It is so named because…
• Cisternography Cisternography is a medical imaging technique to examine the flow of cerebrospinal fluid (CSF) in the brain, and spinal cord. The gold standard for diagnosis…
• Median aperture The median aperture (median aperture of fourth ventricle or foramen of Magendie) is an opening at the caudal portion of the roof of the fourth ventricle…
• Hydrocephalus Hydrocephalus is a condition in which cerebrospinal fluid (CSF) builds up within or around the brain, which can cause pressure to increase in the skull…
• Leptomeningeal cancer Leptomeningeal cancer is a rare complication of cancer in which the disease spreads from the original tumor site to the meninges surrounding the brain…