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Everything about Myalgic encephalomyelitis/chronic fatigue syndrome

Chronic medical condition

Myalgic encephalomyelitis​/​chronic fatigue syndrome (ME/CFS) is a disabling chronic illness. People with ME/CFS experience profound fatigue that does not go away with rest, as well as problems with sleep and memory or concentration. The hallmark symptom is post-exertional malaise (PEM), a worsening of the illness that can start immediately or up to days after even minor physical or mental activity. This "crash" can last hours, days or several months. Further common symptoms include orthostatic intolerance—dizziness or faintness when upright—and pain. Wikipedia →

🧭 Start here: a 6-step reading path

  1. Read the overview: Myalgic encephalomyelitis/chronic fatigue syndromeA 5-minute orientation
  2. Skim a recent paper: Deficient butyrate-producing capacity in the gut microbiome is associated with bacterial network disturbances and fatigue symptoms in ME/CFSInfluential work since 2022
  3. Pick up a classic book: The HauntingThe most-reprinted book on the subject
  4. Read the landmark paper: Convolution PML (CPML): An efficient FDTD implementation of the CFS-PML for arbitrary mediaCited 453 times
  5. Go sideways: Post-exertional malaiseA closely related topic
  6. Go sideways: Clinical descriptions of ME/CFSA closely related topic

đź“– Definitions

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🗂️ The subject at a glance

  1. Classification and terminology
  2. Signs and symptoms
  3. Illness severity
  4. Causes
  5. Pathophysiology
  6. Diagnosis
  7. Management
  8. Prognosis
  9. Epidemiology
  10. History
  11. Society and culture
  12. Research

🏆 Landmark papers (most cited)

🆕 Influential since 2022

đź“š Books worth reading

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đź”— Related topics