Everything about C46

🧭 Start here: a 6-step reading path

1. Read the overview: C46A 5-minute orientation
2. Skim a recent paper: CRISPR/Cas9 genome editing of CCR5 combined with C46 HIV-1 fusion inhibitor for cellular resistant to R5 and X4 tropic HIV-1Influential work since 2022
3. Pick up a classic book: HamletThe most-reprinted book on the subject
4. Read the landmark paper: Preclinical safety and efficacy of an anti–HIV-1 lentiviral vector containing a short hairpin RNA to CCR5 and the C46 fusion inhibitorCited 66 times
5. Go sideways: Escadrille C46A closely related topic
6. Go sideways: Lamb AirA closely related topic

🏆 Landmark papers (most cited)

• Preclinical safety and efficacy of an anti–HIV-1 lentiviral vector containing a short hairpin RNA to CCR5 and the C46 fusion inhibitor

  Orit Wolstein, Maureen Boyd, Michelle Millington · 2014 · Molecular Therapy - Methods & Clinical Development · 66 citations

• Asymmetric Synthesis of Phorboxazole B—Part I: Synthesis of the C20-C38 and C39-C46 Subunits

  David A. Evans, Victor J. Cee, Thomas E. Smith · 2000 · Angewandte Chemie International Edition · 57 citations

• Synthetic studies towards phorboxazole A. A convergent synthesis of the C31C46 polyene oxane-hemiacetal side chain

  Gerald Pattenden, Alleyn T Plowright, James A Tornos · 1998 · Tetrahedron Letters · 53 citations

• Optimization of fermentation medium for a newly isolated yeast strain (Zygosaccharomyces rouxii JM-C46) and evaluation of factors affecting biosynthesis of D-arabitol

  Qi Guo, H. Zabed, Huanhuan Zhang · 2019 · LWT · 48 citations

• Convergent synthesis of the C31C46 domain of the phorboxazole natural products

  Feryan Ahmed, Craig J Forsyth · 1998 · Tetrahedron Letters · 43 citations

• Synthetic studies on ciguatoxin [1]; construction of the spiro acetal part (C46-C55)

  Takahiro Oka, Akio Murai · 1998 · Tetrahedron · 42 citations

• Enantioselective Synthesis of Oasomycin A, Part II: Synthesis of the C29–C46 Subunit

  David A. Evans, Pavel Nagorny, Dominic J. Reynolds · 2007 · Angewandte Chemie International Edition · 36 citations

• Stable Expression of Soluble Therapeutic Peptides in Eukaryotic Cells by Multimerisation: Application to the HIV‐1 Fusion Inhibitory Peptide C46

  Xavier Dervillez, Alexandra Hüther, Jochen Schuhmacher · 2006 · ChemMedChem · 29 citations

🆕 Influential since 2022

• CRISPR/Cas9 genome editing of CCR5 combined with C46 HIV-1 fusion inhibitor for cellular resistant to R5 and X4 tropic HIV-1

  Wannisa Khamaikawin, Chonticha Saisawang, Boonrat Tassaneetrithep · 2024 · Scientific Reports · 20 citations

• Modeling and comparison of solar radiation pressure for two BDS-3 MEO satellites (C45 and C46) with SAR payload

  Jing Guo, Longyu Wang, Chao Yang · 2025 · Advances in Space Research · 11 citations

• A synthesis-enabled relative configurational assignment of the C31–C46 region of hemicalide

  Tegan P. Stockdale, Nelson Y. S. Lam, Ian Paterson · 2022 · Chemical Communications · 5 citations

• C46: Aspects épidémiologiques, diagnostiques et thérapeutiques du cancer du col utérin au service de Radiothérapie de l’Hôpital Dalal Jamm de Dakar

  M B Ba, F N Sarr, F C A Chemega · 2022 · African Journal of Oncology · 1 citations

• C46 A RARE CASE OF LANGERHANS CELLS HISTIOCYTOSIS CARDIO–VASCULAR INVOLVMENT

  M Talarico, S Renne, G Valiante · 2022 · European Heart Journal Supplements · 1 citations

📚 Books worth reading

• HamletWilliam Shakespeare · 1603
• The Call of the WildJack London · 1903
• CatoJoseph Addison, Christine Dunn Henderson · 1713
• HistoriaeP. Cornelius Tacitus · 1852
• Nanhua jingZhuangzi, G. Cox · 1889
• ThermodynamicsYunus A. Çengel, Michael A. Boles · 1989
• The Usborne Illustrated World HistorySusan Peach, Anne Millard · 1990
• Eyewitness Ancient RomeJames, Simon, Simon James · 1997

Ranked by number of editions on Open Library, a rough measure of how lasting a book is.

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