Everything about C17

🧭 Start here: a 6-step reading path

1. Read the overview: C17A 5-minute orientation
2. Skim a recent paper: Atezolizumab plus modified docetaxel, cisplatin, and fluorouracil as first-line treatment for advanced anal cancer (SCARCE C17-02 PRODIGE 60): a randomised, non-comparative, phase 2 studyInfluential work since 2022
3. Pick up a classic book: MetamorfosiThe most-reprinted book on the subject
4. Read the landmark paper: A Review of Odd-Chain Fatty Acid Metabolism and the Role of Pentadecanoic Acid (C15:0) and Heptadecanoic Acid (C17:0) in Health and DiseaseCited 412 times
5. Go sideways: ANSI CA closely related topic
6. Go sideways: C17 (C standard revision)A closely related topic

🏆 Landmark papers (most cited)

• A Review of Odd-Chain Fatty Acid Metabolism and the Role of Pentadecanoic Acid (C15:0) and Heptadecanoic Acid (C17:0) in Health and Disease

  Benjamin Jenkins, James West, Albert Koulman · 2015 · Molecules · 412 citations

• Pharmacology of novel steroidal inhibitors of cytochrome P45017 (17α-hydroxylase/C17–20 lyase)

  S.E. Barrie, G.A. Potter, P.M. Goddard · 1994 · The Journal of Steroid Biochemistry and Molecular Biology · 225 citations

• Ontogeny of expression of the genes for steroidogenic enzymes P450 side-chain cleavage, 3 beta-hydroxysteroid dehydrogenase, P450 17 alpha-hydroxylase/C17-20 lyase, and P450 aromatase in fetal mouse gonads.

  T L Greco, A H Payne · 1994 · Endocrinology · 159 citations

• Expression of cytochrome P450 17alpha-hydroxylase/C17-20 lyase in the fetal rat testis is reduced by maternal exposure to exogenous estrogens.

  G Majdic, R M Sharpe, P J O'Shaughnessy · 1996 · Endocrinology · 132 citations

• Interleukin-1 inhibits Leydig cell steroidogenesis primarily by decreasing 17 alpha-hydroxylase/C17-20 lyase cytochrome P450 expression.

  D B Hales · 1992 · Endocrinology · 126 citations

• Cyclopentanone: A raw material for production of C15 and C17 fuel precursors

  Milan Hronec, Katarína Fulajtárova, Tibor Liptaj · 2014 · Biomass and Bioenergy · 110 citations

• Hormonal Regulation of Cytochrome P450 Enzymes, Cholesterol Side-Chain Cleavage and 17α-Hydroxylase/C17 – 20 Lyase in Leydig Cells1

  Anita H. Payne · 1990 · Biology of Reproduction · 101 citations

• Polymorphisms in the P450 c17 (17-Hydroxylase/17,20-Lyase) and P450 c19 (Aromatase) Genes: Association with Serum Sex Steroid Concentrations and Bone Mineral Density in Postmenopausal Women

  John Somner, Susan McLellan, Joseph Cheung · 2004 · The Journal of Clinical Endocrinology & Metabolism · 100 citations

🆕 Influential since 2022

• Atezolizumab plus modified docetaxel, cisplatin, and fluorouracil as first-line treatment for advanced anal cancer (SCARCE C17-02 PRODIGE 60): a randomised, non-comparative, phase 2 study

  Stefano Kim, Francois Ghiringhelli, Christelle de la Fouchardière · 2024 · The Lancet Oncology · 29 citations

• Design, Synthesis, and Bioevaluation of Novel MyD88 Inhibitor c17 against Acute Lung Injury Derived from the Virtual Screen

  Pan Chen, Ying Zhou, Xiaobo Li · 2023 · Journal of Medicinal Chemistry · 22 citations

• Curcumin inhibits oxidative stress and autophagy in C17 .2 neural stem cell through ERK1 /2 signaling pathways

  Yuting Ruan, Haoyu Luo, Jingyi Tang · 2024 · AGING MEDICINE · 13 citations

• Cotton farming sustainability: Formation of trans-isoeugenol/ bio-aromatics, 5-chloromethylfurfural, C13–C17 liquid hydrocarbons & fertilizer from cotton gin trash

  Vishal Bellie Subramani, Changrong Shi, Lalehvash Moghaddam · 2022 · Journal of Cleaner Production · 12 citations

• Associations between serum pentadecanoic acid (C15:0) and heptadecanoic acid (C17:0) levels and hypertension: a cross-sectional analysis of NHANES data

  Tanping Chen, Jing Luo, Shuai Li · 2025 · Lipids in Health and Disease · 11 citations

📚 Books worth reading

• MetamorfosiOvid, William S. Anderson · 1474
• Cien años de soledadGabriel García Márquez · 1967
• Ars AmatoriaOvid, Niklas Holzberg · 1494
• FastiOvid · 1482
• Meditationes de prima philosophiaRené Descartes · 1642
• A short-title catalogue of books printed in England, Scotland, and Ireland and of English books printed abroadA. W. Pollard, W. A. Jackson · 1926
• Canto generalPablo Neruda · 1943
• Three dialogues between Hylas and PhilonousGeorge Berkeley, George B Berkeley · 1713

Ranked by number of editions on Open Library, a rough measure of how lasting a book is.

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