Everything about Breakpoint

🧭 Start here: a 6-step reading path

1. Read the overview: BreakpointA 5-minute orientation
2. Skim a recent paper: Single-molecular insights into the breakpoint of cellulose nanofibers assembly during saccharificationInfluential work since 2022
3. Pick up a classic book: BreakpointThe most-reprinted book on the subject
4. Read the landmark paper: Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndromeCited 2,874 times
5. Go sideways: DebuggerA closely related topic
6. Go sideways: Stepping (debugging)A closely related topic

🏆 Landmark papers (most cited)

• Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome

  Annemieke J.M.H. Verkerk, Maura Pieretti, James S. Sutcliffe · 1991 · Cell · 2,874 citations

• Cloning of the Chromosome Breakpoint of Neoplastic B Cells with the t(14;18) Chromosome Translocation

  Yoshihide Tsujimoto, Lawrence R. Finger, Jorge Yunis · 1984 · Science · 1,375 citations

• Cloning the chromosomal breakpoint of t(14;18) human lymphomas: clustering around Jh on chromosome 14 and near a transcriptional unit on 18

  Ajay Bakhshi, Jane P. Jensen, Paula Goldman · 1985 · Cell · 861 citations

• The FHIT Gene, Spanning the Chromosome 3p14.2 Fragile Site and Renal Carcinoma–Associated t(3;8) Breakpoint, Is Abnormal in Digestive Tract Cancers

  Masataka Ohta, Hiroshi Inoue, Maria Grazia Cotticelli · 1996 · Cell · 753 citations

• Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome 18.

  M L Cleary, J Sklar · 1985 · Proceedings of the National Academy of Sciences · 611 citations

• A breakpoint map of recurrent chromosomal rearrangements in human neoplasia

  Felix Mitelman, Fredrik Mertens, Bertil Johansson · 1997 · Nature Genetics · 523 citations

• Molecular Cloning of the Chromosomal Breakpoint of B-Cell Lymphomas and Leukemias with the t(11;14) Chromosome Translocation

  Yoshihide Tsujimoto, Jorge Yunis, Louise Onorato-Showe · 1984 · Science · 511 citations

• Molecular Analysis of Acute Promyelocytic Leukemia Breakpoint Cluster Region on Chromosome 17

  Julian Borrow, Audrey D. Goddard, Denise Sheer · 1990 · Science · 478 citations

🆕 Influential since 2022

• Single-molecular insights into the breakpoint of cellulose nanofibers assembly during saccharification

  Ran Zhang, Zhen Hu, Yanting Wang · 2023 · Nature Communications · 91 citations

• Sensitive detection of stage I lung adenocarcinoma using plasma cell-free DNA breakpoint motif profiling

  Wei Guo, Xin Chen, Rui Liu · 2022 · eBioMedicine · 67 citations

• Trichloramine and Hydroxyl Radical Contributions to Dichloroacetonitrile Formation Following Breakpoint Chlorination

  Huang Huang, Hangcong Zheng, Jiajia Jiao · 2022 · Environmental Science & Technology · 46 citations

• The location of the t(4;14) translocation breakpoint within the NSD2 gene identifies a subset of patients with high-risk NDMM

  Nicholas Stong, María Ortiz-Estévez, Fadi Towfic · 2023 · Blood · 45 citations

• A multicenter phase 2 single arm study of cabozantinib in patients with advanced or unresectable renal cell carcinoma pre-treated with one immune-checkpoint inhibitor: The BREAKPOINT trial (Meet-Uro trial 03)

  Giuseppe Procopio, Mélanie Claps, Chiara Pircher · 2022 · Tumori Journal · 45 citations

📚 Books worth reading

• BreakpointRichard A. Clarke · 2006
• Post-Soul Black CinemaWilliam R. Grant · 2004
• Surrounded by EnemiesBryce Zabel · 2013
• 📕Beyond the BreakpointDeborah Faris · 2021
• BreakpointJoAnn Ross · 2009
• 📕BreakpointsLaura Acton · 2020
• 📕BreakpointJon T. Harris · 1998
• Reader's digest condensed books--Volume 4 1978John T. Beaudouin, Nelson DeMille · 1978

Ranked by number of editions on Open Library, a rough measure of how lasting a book is.

🔗 Related topics

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• Stepping (debugging) Program animation or stepping refers to the debugging method of executing code one instruction or line at a time. The programmer may examine the state…
• In-circuit emulation In-circuit emulation (ICE) is the use of a hardware device or in-circuit emulator used to debug the software of an embedded system. It operates by using…
• GNU Debugger The GNU Debugger (GDB) is a portable debugger that runs on many Unix-like systems and works for many programming languages, including Ada, Assembly, C…
• Instruction set simulator An instruction set simulator (ISS) is a simulation model, usually coded in a high-level programming language, which mimics the behavior of a mainframe…
• Function (computer programming) In computer programming, a function (also procedure, method, subroutine, routine, or subprogram) is a callable unit of software logic that has a well-formed…
• X86 debug register On the x86 architecture, a debug register is a register used by a processor for program debugging. There are six debug registers, named DR0...DR7, with…
• Debugging In engineering, debugging is the process of finding the root cause, workarounds, and possible fixes for bugs. For software, debugging tactics can involve…