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Everything about Bipolar disorder

Disorder of depression and mood episodes

Bipolar disorder (BD), previously known as manic depression, is a mental disorder characterized by periods of depression and abnormally elevated mood, lasting days to weeks, and in some cases months. If the elevated mood is severe or associated with psychosis, it is called mania; if it does not significantly affect functioning, it is called hypomania. During mania, an individual behaves or feels abnormally energetic, happy, or irritable, and often makes impulsive and reckless decisions. There is usually sleep disturbance during manic phases. During periods of depression, the individual may experience crying, have a negative outlook, and demonstrate poor eye contact. People with BD are at 11.7 times greater risk of dying by suicide than the general population, although this statistic comes from a collection of studies with high heterogeneity (94.6%). Likewise, approximately 34% attempt suicide during their lifetime but heterogeneity among studies is high (96.4%). Among adolescents with BD, 78% engaged in self-harm. Wikipedia →

🧭 Start here: a 6-step reading path

  1. Read the overview: Bipolar disorderA 5-minute orientation
  2. Skim a recent paper: A systematic review of gut microbiota composition in observational studies of major depressive disorder, bipolar disorder and schizophreniaInfluential work since 2022
  3. Pick up a classic book: Bipolar disorderThe most-reprinted book on the subject
  4. Read the landmark paper: Common polygenic variation contributes to risk of schizophrenia and bipolar disorderCited 4,233 times
  5. Go sideways: Bipolar I disorderA closely related topic
  6. Go sideways: Bipolar II disorderA closely related topic

📖 Definitions

Adjective Involving or having both extremes or poles at the same time.

Adjective Relating to both polar regions.

Adjective Relating to a bipole.

Adjective Relating to or having bipolar disorder.

🗂️ The subject at a glance

  1. Signs and symptoms
  2. Causes
  3. Mechanisms
  4. Diagnosis
  5. Prevention
  6. Management
  7. Prognosis
  8. Epidemiology
  9. Socioeconomic challenges
  10. History
  11. Society and culture
  12. Special populations

🏆 Landmark papers (most cited)

🆕 Influential since 2022

📚 Books worth reading

Ranked by number of editions on Open Library, a rough measure of how lasting a book is.

🔗 Related topics