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Everything about Biosimulation
Biosimulation is a computer-aided mathematical simulation of biological processes and systems and thus is an integral part of systems biology. Due to the complexity of biological systems simplified models are often used, which should only be as complex as necessary. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: BiosimulationA 5-minute orientation
- Skim a recent paper: Synthesis, biosimulation and pharmacological evaluation of benzimidazole derivatives with antihypertensive multitarget effectInfluential work since 2022
- Pick up a classic book: BiosimulationThe most-reprinted book on the subject
- Read the landmark paper: Understanding pharmacokinetics using realistic computational models of fluid dynamics: biosimulation of drug distribution within the CSF space for intrathecal drugsCited 64 times
- Go sideways: LibroadrunnerA closely related topic
- Go sideways: Herbert M. SauroA closely related topic
📖 Definitions
Noun The computer simulation of a biological system
🗂️ The subject at a glance
🏆 Landmark papers (most cited)
Understanding pharmacokinetics using realistic computational models of fluid dynamics: biosimulation of drug distribution within the CSF space for intrathecal drugs
Multiple ontologies in action: Composite annotations for biosimulation models
Surviving the deluge of biosimulation data
Small- and large-scale biosimulation applied to drug discovery and development
Biosimulation of Inflammation and Healing in Surgically Injured Vocal Folds
Application of predictive biosimulation within pharmaceutical clinical development: examples of significance for translational medicine and clinical trial design
Plant-based analogues identified as potential inhibitor against tobacco mosaic virus: A biosimulation approach
Biosimulation of acute phonotrauma: An extended model
🆕 Influential since 2022
Synthesis, biosimulation and pharmacological evaluation of benzimidazole derivatives with antihypertensive multitarget effect
Revisiting Artifacts of Kohn–Sham Density Functionals for Biosimulation
NLIMED: Natural Language Interface for Model Entity Discovery in Biosimulation Model Repositories
CASBERT: BERT-based retrieval for compositely annotated biosimulation model entities
Building a search tool for compositely annotated entities using Transformer-based approach: Case study in Biosimulation Model Search Engine (BMSE)
📚 Books worth reading
- 📕BiosimulationDaniel A. Beard · 2012
Physical chemistry of biological interfacesWillem Norde · 1999
Biosimulation in drug developmentMartin Bertau, Erik Mosekilde · 2007
Biosimulation in biomedical research, health care, and drug developmentErik Mosekilde, Olga Sosnovtseva · 2012
Medicine meets virtual reality 13James D. Westwood · 2005
BiosimulationDaniel A. Beard · 2012
Biosimulation in drug development · 2008- 📕Aspects of the theory of artificial intelligenceInternational Symposium on Biosimulation. 1st, Locarno 1960 · 1962
Ranked by number of editions on Open Library, a rough measure of how lasting a book is.
🔗 Related topics
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