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Everything about BioGRID

Biological database

The Biological General Repository for Interaction Datasets (BioGRID) is a curated biological database of protein-protein interactions, genetic interactions, chemical interactions, and post-translational modifications created in 2003 (originally referred to as simply the General Repository for Interaction Datasets by Mike Tyers, Bobby-Joe Breitkreutz, and Chris Stark at the Lunenfeld-Tanenbaum Research Institute at Mount Sinai Hospital. It strives to provide a comprehensive curated resource for all major model organism species while attempting to remove redundancy to create a single mapping of data. Users of The BioGRID can search for their protein, chemical or publication of interest and retrieve annotation, as well as curated data as reported, by the primary literature and compiled by in house large-scale curation efforts. The BioGRID is hosted in Toronto, Ontario, Canada and Dallas, Texas, United States and is partnered with the Saccharomyces Genome Database, FlyBase, WormBase, PomBase, and the Alliance of Genome Resources. The BioGRID is funded by the NIH and CIHR. BioGRID is an observer member of the International Molecular Exchange Consortium. Wikipedia →

🧭 Start here: a 6-step reading path

  1. Read the overview: BioGRIDA 5-minute orientation
  2. Skim a recent paper: Deciphering Arabidopsis Aquaporin Networks: Comparative Analysis of the STRING and BioGRID InteractomesInfluential work since 2022
  3. Read the landmark paper: BioGRID: a general repository for interaction datasetsCited 3,524 times
  4. Go sideways: ANKRD13CA closely related topic
  5. Go sideways: Human interactomeA closely related topic

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🏆 Landmark papers (most cited)

🆕 Influential since 2022

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