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Everything about Bio-FET

Type of field-effect transistor

A field-effect transistor-based biosensor, also known as a biosensor field-effect transistor, field-effect biosensor (FEB), or biosensor MOSFET, is a field-effect transistor that is gated by changes in the surface potential induced by the binding of molecules. When charged molecules, such as biomolecules, bind to the FET gate, which is usually a dielectric material, they can change the charge distribution of the underlying semiconductor material resulting in a change in conductance of the FET channel. A Bio-FET consists of two main compartments: one is the biological recognition element and the other is the field-effect transistor. The BioFET structure is largely based on the ion-sensitive field-effect transistor (ISFET), a type of metal–oxide–semiconductor field-effect transistor (MOSFET) where the metal gate is replaced by an ion-sensitive membrane, electrolyte solution, and reference electrode. Wikipedia →

🧭 Start here: a 6-step reading path

  1. Read the overview: Bio-FETA 5-minute orientation
  2. Skim a recent paper: A comprehensive review on graphene FET bio-sensors and their emerging application in DNA/RNA sensing & rapid Covid-19 detectionInfluential work since 2022
  3. Pick up a classic book: Intelligent surfaces in biotechnologyThe most-reprinted book on the subject
  4. Read the landmark paper: Conducting polymer nanowires for chemiresistive and FET-based bio/chemical sensorsCited 148 times
  5. Go sideways: Chemical field-effect transistorA closely related topic
  6. Go sideways: ISFETA closely related topic

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🏆 Landmark papers (most cited)

🆕 Influential since 2022

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