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Everything about ASIC2
Protein found in humans
Acid-sensing ion channel 2 (ASIC2) also known as amiloride-sensitive cation channel 1, neuronal (ACCN1) or brain sodium channel 1 (BNaC1) is a protein that in humans is encoded by the ASIC2 gene. The ASIC2 gene is one of the five paralogous genes that encode proteins that form trimeric acid-sensing ion channels (ASICs) in mammals. The cDNA of this gene was first cloned in 1996. The ASIC genes have splicing variants that encode different proteins that are called isoforms. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: ASIC2A 5-minute orientation
- Skim a recent paper: The mechanosensitive ion channel ASIC2 mediates both proprioceptive sensing and spinal alignmentInfluential work since 2022
- Pick up a classic book: 1996 2nd International Conference on ASICThe most-reprinted book on the subject
- Read the landmark paper: Acid‐sensing ion channels ASIC2 and ASIC3 do not contribute to mechanically activated currents in mammalian sensory neuronesCited 241 times
- Go sideways: ASIC1A closely related topic
- Go sideways: ASIC3A closely related topic
📖 Definitions
No dictionary entry for this exact phrase.
🗂️ The subject at a glance
🏆 Landmark papers (most cited)
Acid‐sensing ion channels ASIC2 and ASIC3 do not contribute to mechanically activated currents in mammalian sensory neurones
Acid-sensing Ion Channel 2 (ASIC2) Modulates ASIC1 H+-activated Currents in Hippocampal Neurons
The Ion Channel ASIC2 Is Required for Baroreceptor and Autonomic Control of the Circulation
Knockout of the ASIC2 channel in mice does not impair cutaneous mechanosensation, visceral mechanonociception and hearing
ASIC2 Subunits Target Acid-Sensing Ion Channels to the Synapse via an Association with PSD-95
Localization and behaviors in null mice suggest that ASIC1 and ASIC2 modulate responses to aversive stimuli
Surface Expression of ASIC2 Inhibits the Amiloride-sensitive Current and Migration of Glioma Cells
The acid-sensing ion channel, ASIC2, promotes invasion and metastasis of colorectal cancer under acidosis by activating the calcineurin/NFAT1 axis
🆕 Influential since 2022
The mechanosensitive ion channel ASIC2 mediates both proprioceptive sensing and spinal alignment
βENaC and ASIC2 associate in VSMCs to mediate pressure-induced constriction in the renal afferent arteriole
Investigating role of ASIC2 in synaptic and behavioral responses to drugs of abuse
Potential Implications of Acid-Sensing Ion Channels ASIC2 and ASIC4 in Gonadal Differentiation of Dicentrarchus labrax Subjected to Water Temperature Increase during Gonadal Development
Mice lacking ASIC2 and βENaC are protected from high-fat-diet-induced metabolic syndrome
📚 Books worth reading
1996 2nd International Conference on ASICInternational Conference on ASIC (2nd 1996 Shanghai, China) · 1996
Wireless OFDM systemsMarc Engels · 2002- 📕SMT/ASIC/HybridA. Eder · 1991
Nanometer CMOS ICsHarry Veendrick · 2008
Introduction to reconfigurable supercomputingMarco Lanzagorta · 2009- 📕1996 IEEE 2nd International Conference on Asic · 1997
- 📕1996 IEEE 2nd International Conference on Asic · 1996
- 📕CMOS-5ASIC family 1.2 micron technology product descriptionNEC Electronics (Europe). · 1992
Ranked by number of editions on Open Library, a rough measure of how lasting a book is.
🔗 Related topics
- ASIC1 Acid-sensing ion channel 1 (ASIC1) also known as amiloride-sensitive cation channel 2, neuronal (ACCN2) or brain sodium channel 2 (BNaC2) is a protein…
- ASIC3 Acid-sensing ion channel 3 (ASIC3) also known as amiloride-sensitive cation channel 3 (ACCN3) or testis sodium channel 1 (TNaC1) is a protein that in humans…
- ASIC5 ASIC5 gene is one of the five paralogous genes that encode proteins that form trimeric Acid-sensing ion channels (ASICs) in mammals. Aliases previously…
- ASIC4 Acid-sensing ion channel 4 (ASIC4) also known as amiloride-sensitive cation channel 4 (ACCN4) is a protein that in humans is encoded by the ASIC4 gene…
- SCNN1D The SCNN1D gene encodes for the δ (delta) subunit of the epithelial sodium channel ENaC in vertebrates. ENaC is assembled as a heterotrimer composed of…
- SCNN1A The SCNN1A gene encodes for the α subunit of the epithelial sodium channel ENaC in vertebrates. ENaC is assembled as a heterotrimer composed of three homologous…
- Epithelial sodium channel The epithelial sodium channel (ENaC), also known as amiloride-sensitive sodium channel, is a membrane-bound ion channel that is selectively permeable to…
- SCNN1G The SCNN1G gene encodes for the γ subunit of the epithelial sodium channel ENaC in vertebrates. ENaC is assembled as a heterotrimer composed of three homologous…