Everything about ASB2

🧭 Start here: a 6-step reading path

1. Read the overview: ASB2A 5-minute orientation
2. Skim a recent paper: Skeletal Muscle‐Specific Deletion of E3 Ligase Asb2 Enhances Muscle Mass and StrengthInfluential work since 2022
3. Pick up a classic book: The Red PonyThe most-reprinted book on the subject
4. Read the landmark paper: ASB2 targets filamins A and B to proteasomal degradationCited 91 times
5. Go sideways: ASB1A closely related topic
6. Go sideways: ASB3A closely related topic

🏆 Landmark papers (most cited)

• ASB2 targets filamins A and B to proteasomal degradation

  Mélina L. Heuzé, Isabelle Lamsoul, Massimiliano Baldassarre · 2008 · Blood · 91 citations

• ASB2 Is an Elongin BC-interacting Protein That Can Assemble with Cullin 5 and Rbx1 to Reconstitute an E3 Ubiquitin Ligase Complex

  Mélina L. Heuzé, Florence C. Guibal, Charles A. Banks · 2005 · Journal of Biological Chemistry · 68 citations

• Integrated expression analysis of muscle hypertrophy identifies Asb2 as a negative regulator of muscle mass

  Jonathan R. Davey, Kevin I. Watt, Benjamin L. Parker · 2016 · JCI Insight · 54 citations

• Notch-induced Asb2 expression promotes protein ubiquitination by forming non-canonical E3 ligase complexes

  Lei Nie, Ying Zhao, Wei Wu · 2010 · Cell Research · 43 citations

• AHR Regulates NK Cell Migration via ASB2–Mediated Ubiquitination of Filamin A

  June Ho Shin, Uriel Y. Moreno-Nieves, Luhua H. Zhang · 2021 · Frontiers in Immunology · 29 citations

• High-throughput analysis of the RNA-induced silencing complex in myotonic dystrophy type 1 patients identifies the dysregulation of miR-29c and its target ASB2

  Marisa Cappella, Alessandra Perfetti, Beatrice Cardinali · 2018 · Cell Death & Disease · 24 citations

• The notch pathway promotes NF-κB activation through Asb2 in T cell acute lymphoblastic leukemia cells

  Wei Wu, Li Nie, Li Zhang · 2018 · Cellular & Molecular Biology Letters · 23 citations

• ASB2 is a direct target of FLI1 that sustains NF-κB pathway activation in germinal center-derived diffuse large B-cell lymphoma

  Giulio Sartori, Sara Napoli, Luciano Cascione · 2021 · Journal of Experimental & Clinical Cancer Research · 15 citations

🆕 Influential since 2022

• Skeletal Muscle‐Specific Deletion of E3 Ligase Asb2 Enhances Muscle Mass and Strength

  Hye Rim Jang, Shi‐Young Park, Yeonmi Lee · 2025 · Journal of Cachexia, Sarcopenia and Muscle · 5 citations

• The autophagy receptor NDP52 recruits the E3 ligase ASB2 to mediate NOX4 degradation, suppressing cardiomyocyte ferroptosis and ameliorating heart failure

  Shouguo Yang, Jian Wu, Xiaoyue Song · 2026 · Free Radical Biology and Medicine · 3 citations

• ASB2 inhibits lipid accumulation to promote ILC1 homeostatic fitness and anti-tumor immunity in the mouse liver

  Boqun Bao, Xianwei Wang, Yawen Chen · 2026 · Nature Communications · 0 citations

• Abstract 4012: Triple disruption of CCDC6, CBLB, and ASB2 promotes the therapeutic efficacy of Glypican 3 targeted T cells

  Azlann Arnett, David Steffin, Antonino Montalbono · 2026 · Cancer Research · 0 citations

• Asb2-KIF11 Axis Protects Against Heart Failure by Restoring Lysosomal Distribution and Mitochondrial Homeostasis

  Yicheng Lv, Zhao Sha, Shi Peng · 2026 · Circulation · 0 citations

📚 Books worth reading

• The Red PonyJohn Steinbeck · 1933
• 📕Preaching at the parish communionD. B. Runcorn · 1985
• 📕Asb 2/C + Psalter Dark RedChurch of England Staff · 1980
• 📕Gospel Stamps Yr2 Asb Lect Pkt10 · 1981
• 📕SWI - Schlagwortindex Zu Systematik Für Bibliotheken SFB, Allgemeine Systematik Für öffentliche Bibliotheken ASB, Systematik Stadtbibliothek Duisburg SSD. Teil 2Verein d. Verein d. Bibliothekare an öffentlichen Bibliotheken e.V. (VBB), Marion Beaujean · 2016
• 📕سرمدده (رمان در قصه و حکاىه‌ها)عربزاده، نجم الدىن،, ىوسفى، سهىلا، · 2020
• Fallstudien und Theorie zum Management AccountingOscar A.G. Treyer , Stefan Frischknecht · 2013
• 📕Williams manual of pregnancy complicationsKenneth J. Leveno, James M. Alexander · 2013

Ranked by number of editions on Open Library, a rough measure of how lasting a book is.

🔗 Related topics

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• ASB3 Ankyrin repeat and SOCS box protein 3 is a protein that in humans is encoded by the ASB3 gene. The protein encoded by this gene is a member of the ankyrin…
• ASB13 Ankyrin repeat and SOCS box protein 13 is a protein that in humans is encoded by the ASB13 gene. The protein encoded by this gene is a member of the ankyrin…
• ASB6 Ankyrin repeat and SOCS box protein 6 is a protein that in humans is encoded by the ASB6 gene. The protein encoded by this gene belongs to a family of…
• WSB1 WD repeat and SOCS box-containing protein 1 is a protein that in humans is encoded by the WSB1 gene. This gene encodes a member of the WD-protein subfamily…
• ELOA Elongin A is a protein that in humans is encoded by the ELOA gene. Elongin A is a subunit of the transcription factor B (SIII) complex. The SIII complex…
• SOCS6 Suppressor of cytokine signaling 6 is a protein that in humans is encoded by the SOCS6 gene. The protein encoded by this gene contains a SH2 domain and…
• SOCS5 Suppressor of cytokine signaling 5 is a protein that in humans is encoded by the SOCS5 gene. The protein encoded by this gene contains a SH2 domain and…