Everything about ABL2

🧭 Start here: a 6-step reading path

1. Read the overview: ABL2A 5-minute orientation
2. Skim a recent paper: Circular RNA circPGD contributes to gastric cancer progression via the sponging miR-16-5p/ABL2 axis and encodes a novel PGD-219aa proteinInfluential work since 2022
3. Pick up a classic book: State of Rhode-Island and Providence Plantations. In General Assembly, July 2d session, 1780The most-reprinted book on the subject
4. Read the landmark paper: Arg/Abl2 promotes invasion and attenuates proliferation of breast cancer in vivoCited 107 times
5. Go sideways: Tyrosine-protein kinase ABL1A closely related topic
6. Go sideways: CRKLA closely related topic

🏆 Landmark papers (most cited)

• Arg/Abl2 promotes invasion and attenuates proliferation of breast cancer in vivo

  H Gil-Henn, A Patsialou, Y Wang · 2012 · Oncogene · 107 citations

• COVID-19-driven endothelial damage: complement, HIF-1, and ABL2 are potential pathways of damage and targets for cure

  Monia Marchetti · 2020 · Annals of Hematology · 101 citations

• ABL2/ARG Tyrosine Kinase Mediates SEMA3F-induced RhoA Inactivation and Cytoskeleton Collapse in Human Glioma Cells

  Akio Shimizu, Akiko Mammoto, Joseph E. Italiano · 2008 · Journal of Biological Chemistry · 100 citations

• The cross‐talk between Abl2 tyrosine kinase and TGFβ1 signalling modulates the invasion of clear cell Renal Cell Carcinoma cells

  Sofia De Marco, Barbara Torsello, Emanuela Minutiello · 2022 · FEBS Letters · 73 citations

• miR‐20a Promotes Prostate Cancer Invasion and Migration Through Targeting ABL2

  Xiao‐Fei Qiang, Zheng‐Wei Zhang, Qian Liu · 2014 · Journal of Cellular Biochemistry · 65 citations

• Abl2/Arg Controls Dendritic Spine and Dendrite Arbor Stability via Distinct Cytoskeletal Control Pathways

  Yu-Chih Lin, Mark F. Yeckel, Anthony J. Koleske · 2013 · The Journal of Neuroscience · 61 citations

• A TAZ-AXL-ABL2 Feed-Forward Signaling Axis Promotes Lung Adenocarcinoma Brain Metastasis

  Jacob P. Hoj, Benjamin Mayro, Ann Marie Pendergast · 2019 · Cell Reports · 52 citations

• Direct Interactions with the Integrin β1 Cytoplasmic Tail Activate the Abl2/Arg Kinase

  Mark A. Simpson, William D. Bradley, David Harburger · 2015 · Journal of Biological Chemistry · 43 citations

🆕 Influential since 2022

• Circular RNA circPGD contributes to gastric cancer progression via the sponging miR-16-5p/ABL2 axis and encodes a novel PGD-219aa protein

  Yun Liu, Jia Cao, Linqi Zhu · 2022 · Cell Death Discovery · 21 citations

• Asciminib is a novel inhibitor of ABL1 and ABL2 gene fusions in ALL but requires the ABL SH3 domain for efficacy

  Laura N. Eadie, Elias Lagonik, Elyse C. Page · 2024 · Blood · 15 citations

• Bone mesenchymal stem cell extracellular vesicles delivered miR let-7-5p alleviate endothelial glycocalyx degradation and leakage via targeting ABL2

  Zhe Li, Yuqing Xu, Shiyue Lu · 2023 · Cell Communication and Signaling · 14 citations

• Abl2 repairs microtubules and phase separates with tubulin to promote microtubule nucleation

  Daisy Duan, Wanqing Lyu, Pengxin Chai · 2023 · Current Biology · 11 citations

• Cancer-associated fibroblast-derived exosome Leptin promotes malignant biological lineage in pancreatic ductal adenocarcinoma by regulating ABL2 via miR-224-3p

  Li Zhang, Yesheng Chen, Yihe Dai · 2024 · Molecular Biology Reports · 11 citations

📚 Books worth reading

• 📕State of Rhode-Island and Providence Plantations. In General Assembly, July 2d session, 1780Rhode Island. · 1780
• Literacy challenges for the more ableShelagh Moore · 2004
• Truth Triumphant Through The Spiritual Warfare, Christian Labours, And Writings Of That Able And Faithful Servant Of Jesus Christ, Robert Barclay,Robert Barclay, George Keith · 2015
• Addresses delivered at Agincourt, April 2nd and May 7th, 1878Robert Bradford · 1878
• Able Seaman and LifeboatmanRichard A. Block · 1996
• 📕God Is Able : A Study of 2 Corinthians 9T. S. Thompson · 2020
• 📕An Elegy upon the death of that able and faithful servant of God, Mr. Samuel Sowthen · 1665
• 📕Einigung nach [sektion] 854 Abl. 2 B.G.B.Julian Bach · 1905

Ranked by number of editions on Open Library, a rough measure of how lasting a book is.

🔗 Related topics

• Tyrosine-protein kinase ABL1 Tyrosine-protein kinase ABL1 also known as ABL1 is a protein that, in humans, is encoded by the ABL1 gene (previous symbol ABL) located on chromosome 9…
• CRKL Crk-like protein is a protein that in humans is encoded by the CRKL gene. v-CRK avian sarcoma virus CT10-homolog-like contains one SH2 domain and two SH3…
• SORBS2 ArgBP2 protein, also referred to as Sorbin and SH3 domain-containing protein 2 is a protein that in humans is encoded by the SORBS2 gene. ArgBP2 belongs…
• ABI2 Abl interactor 2 also known as Abelson interactor 2 (Abi-2) is a protein that in humans is encoded by the ABI2 gene. ABI2 has been shown to interact with…
• RAPGEF1 Rap guanine nucleotide exchange factor 1 is a protein that in humans is encoded by the RAPGEF1 gene. The protein encoded by this gene is a human guanine…
• Adapter molecule crk Adapter molecule crk also known as proto-oncogene c-Crk is a protein that in humans is encoded by the CRK gene. The CRK protein participates in the Reelin…
• CBL (gene) E3 ubiquitin-protein ligase CBL is an enzyme that in humans is encoded by the CBL (Casitas B-lineage Lymphoma) gene. CBL gene is the founding member the…
• GRB2 Growth factor receptor-bound protein 2, also known as Grb2, is an adaptor protein involved in signal transduction/cell communication. In humans, the GRB2…