Everything about ABL

🧭 Start here: a 6-step reading path

1. Read the overview: ABLA 5-minute orientation
2. Skim a recent paper: ABL-TC: A lightweight design for network traffic classification empowered by deep learningInfluential work since 2022
3. Pick up a classic book: Seeing VoicesThe most-reprinted book on the subject
4. Read the landmark paper: Efficacy and Safety of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in Chronic Myeloid LeukemiaCited 4,295 times
5. Go sideways: ABAA closely related topic
6. Go sideways: NBC (disambiguation)A closely related topic

🏆 Landmark papers (most cited)

• Efficacy and Safety of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in Chronic Myeloid Leukemia

  Brian J. Druker, Moshe Talpaz, Debra J. Resta · 2001 · New England Journal of Medicine · 4,295 citations

• Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr–Abl positive cells

  Brian J. Druker, Shu Tamura, Elisabeth Buchdunger · 1996 · Nature Medicine · 2,967 citations

• Clinical Resistance to STI-571 Cancer Therapy Caused by BCR-ABL Gene Mutation or Amplification

  Mercedes E. Gorre, Mansoor Mohammed, Katharine Ellwood · 2001 · Science · 2,578 citations

• Activity of a Specific Inhibitor of the BCR-ABL Tyrosine Kinase in the Blast Crisis of Chronic Myeloid Leukemia and Acute Lymphoblastic Leukemia with the Philadelphia Chromosome

  Brian J. Druker, Charles L. Sawyers, Hagop Kantarjian · 2001 · New England Journal of Medicine · 2,226 citations

• Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl.

  S J Martin, C P Reutelingsperger, A J McGahon · 1995 · The Journal of experimental medicine · 2,215 citations

• Induction of Chronic Myelogenous Leukemia in Mice by the P210 bcr/abl Gene of the Philadelphia Chromosome

  George Q. Daley, Richard A. Van Etten, David Baltimore · 1990 · Science · 1,756 citations

• Overriding Imatinib Resistance with a Novel ABL Kinase Inhibitor

  Neil P. Shah, Chris Tran, Francis Y. Lee · 2004 · Science · 1,527 citations

• Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia

  Neil P. Shah, John M. Nicoll, Bhushan Nagar · 2002 · Cancer Cell · 1,357 citations

🆕 Influential since 2022

• ABL-TC: A lightweight design for network traffic classification empowered by deep learning

  Wenting Wei, Huaxi Gu, Wenshuai Deng · 2022 · Neurocomputing · 75 citations

• Targeting BCR-Abl in the treatment of Philadelphia-chromosome positive chronic myelogenous leukemia

  Robert Roskoski · 2022 · Pharmacological Research · 63 citations

• Cell‐Active, Reversible, and Irreversible Covalent Inhibitors That Selectively Target the Catalytic Lysine of BCR‐ABL Kinase

  Peng Chen, Jie Sun, Chengjun Zhu · 2022 · Angewandte Chemie International Edition · 60 citations

• The impact of the BCR-ABL oncogene in the pathology and treatment of chronic myeloid leukemia

  Mohamed El-Tanani, Hamdi Nsairat, Ismail I. Matalka · 2024 · Pathology - Research and Practice · 59 citations

• Mapping the conformational energy landscape of Abl kinase using ClyA nanopore tweezers

  Fanjun Li, Monifa A. Fahie, Kaitlyn M. Gilliam · 2022 · Nature Communications · 59 citations

📚 Books worth reading

• Seeing VoicesOliver Sacks · 1989
• Pooh Goes Visiting and Pooh & Piglet Nearly Catch a WoozleA. A. Milne · 1981
• PowerPeter Morriss · 1987
• Chronic myeloid leukemiaJorge Cortes · 2006
• DisabilityDeborah Marks · 1999
• American sign languageCharlotte Lee Baker-Shenk · 1978
• 📕Chronic Myeloid LeukemiaTariq I. Mughal · 2013
• 📕1-D transient thermal modeling of an ablative material (MCC-1) exposed to a simulated convective Titan 4 launch environmentThomas R. Reinarts · 1998

Ranked by number of editions on Open Library, a rough measure of how lasting a book is.

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