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Everything about 221
Calendar year
Year 221 (CCXXI) was a common year starting on Monday of the Julian calendar. At the time, it was known as the Year of the Consulship of Gratus and Vitellius. The denomination 221 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Wikipedia →
🧭 Start here: a 6-step reading path
- Read the overview: 221A 5-minute orientation
- Skim a recent paper: miR-221/222 as biomarkers and targets for therapeutic intervention on cancer and other diseases: A systematic reviewInfluential work since 2022
- Pick up a classic book: Tao te ChingThe most-reprinted book on the subject
- Read the landmark paper: Conceptualizing the Circular Economy (Revisited): An Analysis of 221 DefinitionsCited 1,336 times
- Go sideways: 220sA closely related topic
- Go sideways: 220A closely related topic
📖 Definitions
No dictionary entry for this exact phrase.
🏆 Landmark papers (most cited)
Conceptualizing the Circular Economy (Revisited): An Analysis of 221 Definitions
Tetrahedron report number 221
MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation
Regulation of the p27Kip1 tumor suppressor by miR‐221 and miR‐222 promotes cancer cell proliferation
RETRACTED: miR-221&222 Regulate TRAIL Resistance and Enhance Tumorigenicity through PTEN and TIMP3 Downregulation
MicroRNA-221/222 Confers Tamoxifen Resistance in Breast Cancer by Targeting p27Kip1
miR-221 and miR-222 Expression Affects the Proliferation Potential of Human Prostate Carcinoma Cell Lines by Targeting p27Kip1
miR-221 overexpression contributes to liver tumorigenesis
🆕 Influential since 2022
miR-221/222 as biomarkers and targets for therapeutic intervention on cancer and other diseases: A systematic review
Safety and activity of the first-in-class locked nucleic acid (LNA) miR-221 selective inhibitor in refractory advanced cancer patients: a first-in-human, phase 1, open-label, dose-escalation study
METTL3 mediates Ang-II-induced cardiac hypertrophy through accelerating pri-miR-221/222 maturation in an m6A-dependent manner
Strained Pt(221) Facet in a PtCo@Pt-Rich Catalyst Boosts Oxygen Reduction and Hydrogen Evolution Activity
IgE-neutralizing UB-221 mAb, distinct from omalizumab and ligelizumab, exhibits CD23-mediated IgE downregulation and relieves urticaria symptoms
📚 Books worth reading
Tao te Ching老子, Yang Peng · 1842
Shi jiSima Qian, Burton Watson · 1550
Guo yuMing Zuoqiu · 1927
A course in phoneticsPeter Ladefoged · 1975- 📕Wu Yue chun qiuYe Zhao · 1668
Vowels and ConsonantsPeter Ladefoged · 2000
WuJonathan Clements · 2007
China's Southern Tang dynasty, 937-976Johannes L. Kurz · 2011
Ranked by number of editions on Open Library, a rough measure of how lasting a book is.
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