Everything about 16

🧭 Start here: a 6-step reading path

1. Read the overview: 16A 5-minute orientation
2. Skim a recent paper: Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022Influential work since 2022
3. Pick up a classic book: The Giving TreeThe most-reprinted book on the subject
4. Read the landmark paper: Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion ImagingCited 4,749 times
5. Go sideways: Zero (disambiguation)A closely related topic
6. Go sideways: WinnerA closely related topic

🏆 Landmark papers (most cited)

• Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging

  Gregory W. Albers, Michael P. Marks, Stephanie Kemp · 2018 · New England Journal of Medicine · 4,749 citations

• Body fat assessed from total body density and its estimation from skinfold thickness: measurements on 481 men and women aged from 16 to 72 Years

  J. V. G. A. Durnin, J. Womersley · 1974 · British Journal of Nutrition · 4,563 citations

• The 16-Item quick inventory of depressive symptomatology (QIDS), clinician rating (QIDS-C), and self-report (QIDS-SR): a psychometric evaluation in patients with chronic major depression

  A.John Rush, Madhukar H Trivedi, Hicham M Ibrahim · 2003 · Biological Psychiatry · 3,391 citations

• The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

  Martin Scheffner, Bruce A. Werness, Jon M. Huibregtse · 1990 · Cell · 3,292 citations

• miR-15 and miR-16 induce apoptosis by targeting BCL2

  Amelia Cimmino, George Adrian Calin, Muller Fabbri · 2005 · Proceedings of the National Academy of Sciences · 2,987 citations

• Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis

  T. J. Kwiatkowski, D. A. Bosco, A. L. LeClerc · 2009 · Science · 2,408 citations

• The Human Papilloma Virus-16 E7 Oncoprotein Is Able to Bind to the Retinoblastoma Gene Product

  Nicholas Dyson, Peter M. Howley, Karl Münger · 1989 · Science · 2,315 citations

• High-spin molecules: [Mn12O12(O2CR)16(H2O)4]

  Roberta Sessoli, Hui Lien Tsai, Ann R. Schake · 1993 · Journal of the American Chemical Society · 2,216 citations

🆕 Influential since 2022

• Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022

  John P. Thornhill, Sapha Barkati, Sharon Walmsley · 2022 · New England Journal of Medicine · 1,970 citations

• Prevalence and Early Identification of Autism Spectrum Disorder Among Children Aged 4 and 8 Years — Autism and Developmental Disabilities Monitoring Network, 16 Sites, United States, 2022

  Kelly A. Shaw, Susan Williams, Mary E. Patrick · 2025 · MMWR. Surveillance Summaries · 968 citations

• Efficacy, durability, and safety of intravitreal faricimab up to every 16 weeks for neovascular age-related macular degeneration (TENAYA and LUCERNE): two randomised, double-masked, phase 3, non-inferiority trials

  Jeffrey S Heier, Arshad M Khanani, Carlos Quezada Ruiz · 2022 · The Lancet · 781 citations

• Establishing reaction networks in the 16-electron sulfur reduction reaction

  Rongli Liu, Ziyang Wei, Lele Peng · 2024 · Nature · 595 citations

• A Comprehensive Study of Galaxies at z ∼ 9–16 Found in the Early JWST Data: Ultraviolet Luminosity Functions and Cosmic Star Formation History at the Pre-reionization Epoch

  Yuichi Harikane, Masami Ouchi, Masamune Oguri · 2023 · The Astrophysical Journal Supplement Series · 548 citations

📚 Books worth reading

• The Giving TreeShel Silverstein, Kjell Hill Silverstein · 1963
• What is history?Edward Hallet Carr · 1961
• A People's History of the United StatesHoward Zinn, Kathy Emery · 1980
• The Tales of Beedle the BardJ. K. Rowling · 2008
• Girl in PiecesKathleen Glasgow · 2000
• The Viscount Who Loved MeJulia Quinn · 2000
• Crooked KingdomLeigh Bardugo · 2016
• A Slow Regard of Silent ThingsPatrick Rothfuss · 2013

Ranked by number of editions on Open Library, a rough measure of how lasting a book is.

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